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PRALATREXATE

SynDRA canonical compound SYN0023599 — structure-anchored drug synonym record

All known targets

• DHFR
• SLC19A1
• FOLR1
• PDF
• SLC46A1

Mechanisms of action (all sources)

• dihydrofolate reductase inhibitor
• PDF INHIBITOR

Drug classes

• Folate Analog Metabolic Inhibitor

ATC classes

• L01B · ANTIMETABOLITES

Cross-references

• PubChem CID: 148121
• ChEMBL: CHEMBL1201746
• DrugBank: DB06813
• ChEBI: CHEBI:71223
• KEGG: D05589
• RxNorm: 662019
• Wikipedia: Pralatrexate
• TTD: D02LWU
• LINCS BRD: BRD-A74914197

Synonyms

• 10-Propargyl-10-deazaaminopterin
• folotyn
• Pralatrexato
• NSC-754230
• PDX
• Folotyn
• Folotyn (TN)
• HSDB 7786
• Pralatrexate(Folotyn)
• CHEBI:71223
• N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid
• NSC 754230
• (2S)-2-(4-(1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzamido)pentanedioic acid
• A8Q8I19Q20
• 146464-95-1 (racemic)
• NSC754230
• L-Glutamic acid, N-[4-[1-[(2,4-diamino-6-pteridinyl)methyl]-3-butyn-1-yl]benzoyl]-
• (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid
• NCGC00242596-01
• (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid
• (2S)-2-[[4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl]amino]pentanedioic acid
• N-{4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}-L-glutamic acid
• L-Glutamic acid, N-(4-(1-((2,4-diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-
• N -(4-{1-[(2,4-diaminopteridin-6-yl)methyl]but-3-yn-1-yl}benzoyl)-L-glutamic acid
• (2S)-2-[[4-[(1RS)-1-[(2,4-diaminopteridin-6-yl)methyl]but-3-ynyl]benzoyl]amino]pentanedioic acid
• Pralatrexate [USAN]
• Pralatrexate [USAN:INN]
• pralatrexato
• pralatrexatum
• Pralatrexat
• Pralatrexte
• UNII-A8Q8I19Q20
• PRALATREXATE [MI]
• PRALATREXATE [INN]
• PRALATREXATE [JAN]
• PRALATREXATE [HSDB]
• PRALATREXATE [VANDF]
• SCHEMBL21633