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PITAVASTATIN

SynDRA canonical compound SYN0023604 — structure-anchored drug synonym record

All known targets

• HMGCR
• APOA1
• CYP2C8
• NR4A2
• RXRA

Mechanisms of action (all sources)

• HMGCR INHIBITOR
• HMG-CoA reductase inhibitor

Drug classes

• Hydroxymethylglutaryl-CoA Reductase Inhibitors
• HMG-CoA Reductase Inhibitor
• Anticholesteremic Agents
• Antimetabolites
• Enzyme Inhibitors
• Hypolipidemic Agents
• Lipid Regulating Agents

ATC classes

• C10A · LIPID MODIFYING AGENTS, PLAIN

Cross-references

• PubChem CID: 5282452
• ChEMBL: CHEMBL1201753
• DrugBank: DB08860
• ChEBI: CHEBI:32020
• KEGG: D01862
• RxNorm: 861634
• PDB: PV9
• Wikipedia: Pitavastatin
• TTD: D0G1WL
• LINCS BRD: BRD-K30097969

Synonyms

• nisvastatin
• itavastatin
• pitavastatin calcium hydrate
• pitavastatin calcium
• livalo
• Pitavastatine
• Pitavastatina
• NSC-760423
• Pitavastatin component of k-924 pivastatin
• PITAVASTATIN CALCIUM
• Livalo
• Pitavastatin hemicalcium
• NK-104
• Nisvastatin
• UNII-IYD54XEG3W
• Flovas
• IYD54XEG3W
• 2C25H23FNO4Ca
• CHEBI:71258
• NK 104 (acid)
• Calcium (3R,5S,E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoate
• AK-50694
• Itavastatin calcium
• Bis((3R,5S,6E)-7-(2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl)-3,5-dihydroxy-6-heptenoate), monocalcium salt
• Pitavastatin calcium (JAN)
• Alipza
• Livazo
• P 872441
• 6-Heptenoic acid,
• Itavastatin
• Pitavastatin [INN]
• Pitavastatin calcium
• (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid
• CHEBI:32020
• M5681Q5F9P
• (3R,5S,6E)-7-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoic acid
• NSC 760423
• (3R,5S,6E)-7-(2-Cyclopropyl-4-(p-fluorophenyl)-3-quinolyl)-3,5-dihydroxy-6-heptenoic acid

Reported adverse events

• Constipation
• Hypersensitivity
• Myalgia
• Myopathy
• Pain in extremity
• Rhabdomyolysis
• Virologic failure
• Back pain
• Pain