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RUFINAMIDE
SynDRA canonical compound SYN0023605 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · Rx/OTC |
| Primary target(s) | SCN9A |
| Mechanism of action | Voltage-gated sodium channel blocker |
| Indication | seizures |
| Disease area | neurology/psychiatry |
All known targets
- SCN1A
- SCN3A
- SCN9A
- SCN10A
- SCN11A
- SCN2A
- SCN4A
- SCN5A
- SCN7A
- SCN8A
- CA5A
- CYP2E1
Mechanisms of action (all sources)
- Voltage-gated sodium channel blocker
- SCN1A BLOCKER
- Sodium channel alpha subunit blocker
- SCN5A BLOCKER
- SCN4A BLOCKER
- SCN7A BLOCKER
- SCN2A BLOCKER
- SCN9A BLOCKER
- SCN3A BLOCKER
- SCN11A BLOCKER
- SCN8A BLOCKER
- SCN10A BLOCKER
Drug classes
- Anticonvulsants
- Cardiovascular Agents
- Central Nervous System Agents
- Membrane Transport Modulators
- Sodium Channel Blockers
- Voltage-Gated Sodium Channel Blockers
ATC classes
Cross-references
Synonyms
- inovelon
- banzel
- CGP 33101
- Rufinamida
- 60231/4
- CGP-33101
- E-2080
- E2080
- RUF-331
- Banzel
- Inovelon
- 1-(2,6-Difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide
- Cgp 33101
- Xilep
- 1-[(2,6-difluorophenyl)methyl]-1H-1,2,3-Triazole-4-carboxamide
- RUF 331
- UNII-WFW942PR79
- 1-[(2,6-difluorophenyl)methyl]triazole-4-carboxamide
- WFW942PR79
- C10H8F2N4O
- POGQSBRIGCQNEG-UHFFFAOYSA-N
- 1H-1,2,3-Triazole-4-carboxamide, 1-[(2,6-difluorophenyl)methyl]-
- NCGC00165883-02
- DSSTox_CID_26506
- DSSTox_RID_81675
- DSSTox_GSID_46506
- Banzel, Rufinamide
- SYN-111
- Rufinamide (USAN/INN)
- Inovelon/Banzel
- rufinamide (usp-rs)
- E 2080
- rufinamide (usp monograph)
- DTXCID9026506
- 1-((2,6-difluorophenyl)methyl)triazole-4-carboxamide
- rufinamidum
- RefChem:57756
- SYN11
Reported adverse events
- Constipation
- Diplopia
- Dizziness
- Fatigue
- Headache
- Hypersensitivity
- Nausea
- Rash
- Somnolence
- Vomiting
- Aggression
- Anxiety
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