← SynDRA

FORETINIB

SynDRA canonical compound SYN0024164 — structure-anchored drug synonym record

All known targets

• KDR
• MET
• FLT1
• FLT4
• FLT3
• KIT
• TEK
• AXL
• MST1R
• PDGFRA
• PDGFRB

Mechanisms of action (all sources)

• VEGFR inhibitor
• FLT3 INHIBITOR
• Tyrosine-protein kinase receptor FLT3 inhibitor
• KIT INHIBITOR
• Stem cell growth factor receptor inhibitor
• MET INHIBITOR
• Hepatocyte growth factor receptor inhibitor
• PDGFRB INHIBITOR
• Platelet-derived growth factor receptor inhibitor
• PDGFRA INHIBITOR
• TEK INHIBITOR
• Tyrosine-protein kinase TIE-2 inhibitor

Cross-references

• PubChem CID: 42642645
• ChEMBL: CHEMBL1230609
• DrugBank: DB12307
• ChEBI: 91418
• PDB: 88Z
• Wikipedia: Foretinib
• TTD: D0D1GF
• LINCS BRD: BRD-K03449891

Synonyms

• GSK-1363089
• Gsk1363089
• EXEL-2880
• GSK-089
• GSK-1363089G
• GSK089
• GSK1363089G
• XL-880
• XL880
• GSK 089
• GSK 1363089
• GSK1363089
• XL 880
• GSK1363089, GSK089, foretinib, EXEL-2880, XL880
• 88Z
• MET inhibitors
• EXEL 2880
• Foretinib (GSK1363089)
• Foretinib(XL880)
• 81FH7VK1C4
• GSK 1363089G
• N-[3-Fluoro-4-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinolinyl]oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide
• n-(3-fluoro-4-((6-methoxy-7-(3-(4-morpholinyl)propoxy)-4-quinolinyl)oxy)phenyl)-n'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide
• N-(3-Fluoro-4-{[6-Methoxy-7-(3-Morpholin-4-Ylpropoxy)quinolin-4-Yl]oxy}phenyl)-N'-(4-Fluorophenyl)cyclopropane-1,1-Dicarboxamide
• N-[3-fluoro-4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quinolin-4-yl}oxy)phenyl]-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
• N-(3-Fluoro-4-((6-methoxy-7-(3-(morpholin-4-yl)propoxy)quinolin-4-yl)oxy)phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
• N-[3-fluoro-4-({6-(methyloxy)-7-[(3-morpholin-4-ylpropyl)oxy]quinolin-4-yl]oxy)phenyl}-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
• N-[3-fluoro-4-({6-(methyloxy)-7-[(3-morpholin 4-ylpropyl)oxy]quinolin-4-yl}oxy)phenyl]-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
• xl-880, Foretinib
• FORETINIB [INN]
• Foretinib (USAN/INN)
• Foretinib [USAN:INN]
• FORETINIB [USAN]
• FORETINIB [WHO-DD]
• UNII-81FH7VK1C4
• MLS006010302
• SCHEMBL371804
• Foretinib - GSK1363089