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AZD-1480

SynDRA canonical compound SYN0024187 — structure-anchored drug synonym record

All known targets

• JAK2
• JAK1
• JAK3

Mechanisms of action (all sources)

• JAK inhibitor
• JAK2 INHIBITOR
• Tyrosine-protein kinase JAK2 inhibitor
• JAK2 MODULATOR

Cross-references

• PubChem CID: 16659841
• ChEMBL: CHEMBL1231124
• DrugBank: DB12588
• PDB: AZ5
• TTD: D0MP0X
• LINCS BRD: BRD-K65928735

Synonyms

• AZD1480
• RET inhibitors
• AZD 1480
• UNII-KL2Z2TLF01
• (S)-5-chloro-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
• KL2Z2TLF01
• CHEMBL1231124
• 5-Chloro-N2-[(1s)-1-(5-Fluoropyrimidin-2-Yl)ethyl]-N4-(5-Methyl-1h-Pyrazol-3-Yl)pyrimidine-2,4-Diamine
• 2,4-Pyrimidinediamine, 5-chloro-N2-((1S)-1-(5-fluoro-2-pyrimidinyl)ethyl)-N4-(5-methyl-1H-pyrazol-3-yl)-
• C14H14ClFN8
• 2xa4
• MLS006011153
• GTPL5933
• SCHEMBL3345019
• DTXSID50239469
• EX-A450
• AZD 1480 [WHO-DD]
• BCPP000361
• BCP02413
• AZD1480,AZD 1480
• BDBM50335201
• NSC756648
• NSC799344
• s2162
• ZINC58631551
• AKOS027322548
• AM85979
• BCP9000361
• CCG-268021
• DB12588
• NSC-756648
• NSC-799344
• NCGC00242486-01
• NCGC00242486-02
• NCGC00242486-05
• 2,4-Pyrimidinediamine,5-chloro-N2-[(1S)-1-(5-fluoro-2-pyrimidinyl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)-
• 5-Chloro-N2-[(1S)-1-(5-fluoro-2-pyrimidinyl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)-2,4-pyrimidinediamine
• AC-32807