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PEVONEDISTAT

SynDRA canonical compound SYN0024188 — structure-anchored drug synonym record

All known targets

• NAE1
• UBA3
• NAE1; UBA3
• NEDD8

Mechanisms of action (all sources)

• UBA3 INHIBITOR
• NEDD8 activating enzyme inhibitor
• NAE1 INHIBITOR
• nedd activating enzyme inhibitor
• Modulator
• NEDD8 INHIBITOR

Drug classes

• Enzyme Inhibitors

Cross-references

• PubChem CID: 16720766
• ChEMBL: CHEMBL1231160
• DrugBank: DB11759
• ChEBI: 95028
• KEGG: D10413
• PDB: B39
• Wikipedia: Pevonedistat
• TTD: D0ZD2M
• LINCS BRD: BRD-K67844266

Synonyms

• MLN-4924
• MLN-4924003
• MLN4924
• PEVONEDISTAT (MLN4924)
• UNII-S3AZD8D215
• MLN 4924
• S3AZD8D215
• Sulfamic acid [(1S,2S,4R)-4-[4-[[(1S)-2,3-dihydro-1H-inden-1-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxycyclopentyl]methyl ester
• ((1S,2S,4R)-4-(4-(((S)-2,3-dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate
• C21H25N5O4S
• [(1s,2s,4r)-4-{4-[(1s)-2,3-Dihydro-1h-Inden-1-Ylamino]-7h-Pyrrolo[2,3-D]pyrimidin-7-Yl}-2-Hydroxycyclopentyl]methyl Sulfamate
• Pevonedistat [USAN:INN]
• 3gzn
• Pevonedistat (MLN-4924)
• 905579-51-3 (free base)
• Pevonedistat (USAN)
• PEVONEDISTAT [USAN]
• ((1S,2S,4R)-4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate
• Sulfamic acid, ((1S,2S,4R)-4-(4-(((1S)-2,3-dihydro-1H-inden-1-yl)amino)-7H-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl ester
• pevonedistatum
• ((1S,2S,4R)-4-{4-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl)methyl sulfamate
• B39
• Pevonedistat; MLN4924
• PEVONEDISTAT [INN]
• ((1S,2S,4R)-4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulphamate
• MLS006010830
• PEVONEDISTAT [WHO-DD]
• SCHEMBL192875
• TAK924
• CHEMBL1231160
• CHEBI:95028
• GTPL12117
• TAK-924
• CHEBI:145535
• DTXSID701022549
• EX-A1472
• BDBM50285607
• NSC793435