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PIRFENIDONE
SynDRA canonical compound SYN0024630 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | TNF |
|---|
| Mechanism of action | TGF beta receptor inhibitor |
|---|
| Indication | idiopathic pulmonary fibrosis (IPF) |
|---|
| Disease area | pulmonary |
|---|
All known targets
- TNF
- FURIN
- MAPK14
- TGFB1
- TNFRSF1A
Mechanisms of action (all sources)
- TGF beta receptor inhibitor
- TGFB1 MODULATOR
Drug classes
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antineoplastic Agents
- Antirheumatic Agents
- Central Nervous System Agents
- Peripheral Nervous System Agents
- Sensory System Agents
- Pyridone
ATC classes
- L04A · IMMUNOSUPPRESSANTS
Cross-references
Synonyms
- esbriet
- glaspia
- Pirfenidona
- Pirespa
- AMR-69
- NSC-748456
- Esbriet
- Pirfenidone axunio (previously pirfenidone aet)
- Pirfenidone component of esbriet
- Pirfenidone viatris
- Deskar
- Pirfenidonum
- P 2116
- F-647
- KS-5041
- Pirfenidona [INN-Spanish]
- Pirfenidone (Deskar)
- Pirfenidone [USAN:INN]
- Pirfenidonum [INN-Latin]
- S-7701
- Pirfenidone (JAN/USAN/INN)
- 5-Methyl-1-phenyl-1H-pyridin-2-one
- 5-Methyl-1-phenyl-2(1H)-pyridone
- 5-Methyl-1-phenyl-2-(1H)-pyridone
- 5-methyl-1-phenylpyridin-2(1H)-one
- 5-methyl-1-phenylpyridin-2-one
- ESBRIET COMPONENT PIRFENIDONE
- 2(1H)-Pyridinone, 5-methyl-1-phenyl-
- pirfenidone (ep monograph)
- NSC 748456
- D7NLD2JX7U
- AMR 69
- DTXCID2025183
- CHEBI:32016
- 5-METHYL-1-PHENYL-1,2-DIHYDROPYRIDIN-2-ONE
- RefChem:58560
- L04AX05
- 5-methyl-1-phenyl-2(1H)-pyridinone
Reported adverse events
- Agranulocytosis
- Headache
- Angioedema
- Dyspepsia
- Fatigue
- Insomnia
- Rash
- Arthralgia
- Drug-induced liver injury
- Dizziness
- Vomiting
- Nausea
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