TYRPHOSTIN AG 490

SynDRA canonical compound SYN0024738 — structure-anchored drug synonym record

Clinical phase	Preclinical
Primary target(s)	EGFR \| JAK2 \| JAK3 \| STAT3
Mechanism of action	EGFR inhibitor \| JAK inhibitor

All known targets

JAK2
JAK3
EGFR
STAT3

Mechanisms of action (all sources)

EGFR INHIBITOR
JAK inhibitor
JAK2 INHIBITOR
JAK3 INHIBITOR

Cross-references

PubChem CID: 5328779
ChEMBL: CHEMBL1257042
ChEBI: 131968
TTD: D0GZ7B

Synonyms

AG490
(E)-N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamide
AG 490
Tyrphostin B42
tyrphostin AG-490
Tyrphostin AG490
AG-490 (Tyrphostin B42)
alpha-Cyano-(3,4-dihydroxy)-N-benzylcinnamide
N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamide
(2E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
CHEMBL56543
(E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
(2E)-2-CYANO-3-(3,4-DIHYDROXYPHENYL)-N-(PHENYLMETHYL)-2-PROPENAMIDE
SMR001230665
(Z)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
2-Cyano-3-(3,4-dihydroxyphenyl)-N-(benzyl)-2-propenamide
Tyrphostin B 42
(E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamide
SCHEMBL17743575
CHEBI:92212
AKOS005146338
AC-28414
BRD-K12357156-001-01-5

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