← SynDRA

LENVATINIB

SynDRA canonical compound SYN0024932 — structure-anchored drug synonym record

All known targets

• KDR
• FLT4
• FLT1
• FGFR1
• KIT
• RET
• PDGFRB
• PDGFB
• MAPKAPK2
• NQO2
• ABL1
• PDGFRA

Mechanisms of action (all sources)

• KIT INHIBITOR
• FGFR inhibitor
• PDGFR inhibitor
• VEGFR inhibitor
• FLT1 INHIBITOR
• Vascular endothelial growth factor receptor inhibitor
• FLT4 INHIBITOR
• KDR INHIBITOR
• PDGFR tyrosine kinase receptor inhibitor
• RET INHIBITOR
• PDGFRA INHIBITOR
• FGFR1 INHIBITOR

Drug classes

• Receptor Tyrosine Kinase Inhibitors
• Antineoplastic Agents
• Enzyme Inhibitors
• Protein Kinase Inhibitors
• Kinase Inhibitor

ATC classes

• L01E · PROTEIN KINASE INHIBITORS

Cross-references

• PubChem CID: 9823820
• ChEMBL: CHEMBL1289601
• DrugBank: DB09078
• ChEBI: CHEBI:85994
• KEGG: D09919
• RxNorm: 1603296
• PDB: LEV
• Wikipedia: Lenvatinib
• TTD: D0R0FO
• LINCS BRD: BRD-K39974922

Synonyms

• E 7080
• lenvima
• ER-203492-00
• E7080
• lenvatinib mesylate
• lenvatinib mesilate
• E-7080
• Kisplyx
• E-7080, E7080
• 4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxy-quinoline-6-carboxamide
• E7080 (Lenvatinib)
• 4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxamide
• Lenvatinib (E7080)
• Lenvatinib free base
• 4-{3-Chloro-4-[(Cyclopropylcarbamoyl)amino]phenoxy}-7-Methoxyquinoline-6-Carboxamide
• UNII-EE083865G2
• 4-[3-Chloro-4-(cyclopropylaminocarbonyl)aminophenoxy]-7-methoxy-6-quinolinecarboxamide
• 4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide
• CHEMBL1289601
• CHEBI:85994
• 417716-92-8 (free base)
• EE083865G2
• 4-(3-chloro-4-(N'-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxamide
• 4-(3-chloro-4-((cyclopropylaminocarbonyl)amino)phenoxy)-7-methoxy-6-quinolinecarboxamide
• 4-[3-Chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide
• Lenvatinib [USAN]
• Lenvatinib [USAN:INN]
• 4-(3-CHLORO-4-((CYCLOPROPYLCARBAMOYL)AMINO)PHENOXY)-7-METHOXYQUINOLINE-6-CARBOXAMIDE
• 4-(3-Chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide
• LEV
• Lenvatinib; E7080
• LENVATINIB [MI]
• Lenvatinib base- Bio-X
• LENVATINIB [INN]
• Lenvatinib (USAN/INN)
• LENVATINIB [WHO-DD]
• MLS006011239
• SCHEMBL864638

Reported adverse events

• Alopecia
• Arthralgia
• Constipation
• Dehydration
• Dizziness
• Dry mouth
• Dysgeusia
• Dyspepsia
• Dysphonia
• Fatigue
• Headache
• Hepatotoxicity