DOTHIEPIN

SynDRA canonical compound SYN0025417 — structure-anchored drug synonym record

Clinical phase	Launched
Primary target(s)	CHRM1 \| CHRM2 \| CHRM3 \| CHRM4 \| CHRM5 \| CYP2C19 \| HRH1 \| SLC6A2 \| SLC6A4
Mechanism of action	norepinephrine reuptake inhibitor \| serotonin–norepinephrine reuptake inhibitor (SNRI) \| tricyclic antidepressant
Indication	depression
Disease area	neurology/psychiatry

All known targets

CHRM1
CHRM2
CHRM3
CHRM4
CHRM5
HRH1
SLC6A2
SLC6A4
ADRA1A
ADRA2B
CYP2C19
HTR2A

Mechanisms of action (all sources)

norepinephrine reuptake inhibitor
serotonin–norepinephrine reuptake inhibitor (SNRI)
tricyclic antidepressant
SLC6A4 INHIBITOR
SLC6A2 INHIBITOR

Drug classes

Adrenergic Agents
Adrenergic Uptake Inhibitors
Antidepressive Agents
Antidepressive Agents, Tricyclic
Central Nervous System Agents
Membrane Transport Modulators
Neurotransmitter Agents
Neurotransmitter Uptake Inhibitors
Psychotropic Drugs

ATC classes

ANTIDEPRESSANTS

Cross-references

PubChem CID: 5284550
ChEMBL: CHEMBL1492500
DrugBank: DB09167
ChEBI: CHEBI:36798
KEGG: D01546
Wikipedia: Dosulepin
TTD: D0Q2MN

Synonyms

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