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DOXEPIN
SynDRA canonical compound SYN0025789 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SLC6A4 |
|---|
| Mechanism of action | Histamine receptor antagonist |
|---|
| Indication | anxiety | depression |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- HRH1
- SLC6A4
- SLC6A2
- HRH2
- Htr3b
- Htr1b
- Htr1d
- Htr1f
- Htr2a
- Htr2b
- Htr2c
- Htr3a
Mechanisms of action (all sources)
- Histamine receptor antagonist
- HRH1 ANTAGONIST
- Histamine H1 receptor antagonist
- SLC6A2 INHIBITOR
- SLC6A4 INHIBITOR
Drug classes
- Antidepressive Agents
- Antidepressive Agents, Tricyclic
- Central Nervous System Agents
- Central Nervous System Depressants
- Histamine Agents
- Histamine Antagonists
- Hypnotics and Sedatives
- Neurotransmitter Agents
- Psychotropic Drugs
- Sleep Aids, Pharmaceutical
- Tricyclic Antidepressant
ATC classes
- D04A · ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
- N06A · ANTIDEPRESSANTS
Cross-references
Synonyms
- P-3693A
- doxepine
- doxepin hydrochloride
- silenor
- doxepin HCl
- Doxepine
- Doxepina
- Sinepin
- Sinequan
- Zonalon
- Doxepinum [INN-Latin]
- Doxepina [INN-Spanish]
- Doxepin [USAN]
- trans-doxepin
- (e)-doxepin
- Quitaxon
- MF 10
- UNII-851NLB57HQ
- CCRIS 9176
- HSDB 3069
- Sinequan (TN)
- Cidoxepina
- Cidoxepinum
- 851NLB57HQ
- 11-(3-(Dimethylamino)propylidene)-6H-dibenz(b,e)oxepine
- 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenz(b,e)oxipin
- 11-(3-Dimethylamino-propyliden)-6,11-dihydro-dibenz(b,e)oxipin
- N,N-Dimethyldibenz(b,e)oxepin-delta(11(6H),gamma)-propylamine
- Cidoxepin [INN]
- Curatin
- Adapin
- Cidoxepin
- Doxepinum
- Triadapin
- Doxepin Hydrochloride
- MOLI001594
- Adapine (TN)
- Aponal (TN)
Reported adverse events
- Nausea
- Dizziness
- Dry mouth
- Eosinophilia
- Hypertension
- Sedation
- Insomnia
- Gastroenteritis
- Infection
- Nasopharyngitis
- Somnolence
- QRS axis
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