BARDOXOLONE METHYL

SynDRA canonical compound SYN0026804 — structure-anchored drug synonym record

Clinical phase	Phase 3
Primary target(s)	BCL2 \| CHUK \| GSR \| HMOX1 \| HMOX2 \| NFE2L2 \| PPARG \| STAT3
Mechanism of action	nuclear factor erythroid derived, like (NRF2) activator

All known targets

PPARG
BCL2
CHUK
GSR
HMOX1
HMOX2
IKBKB
NFE2L2
STAT3

Mechanisms of action (all sources)

PPARG ANTAGONIST
Peroxisome proliferator-activated receptor gamma antagonist
IKBKB INHIBITOR
Inhibitor of nuclear factor kappa B kinase beta subunit inhibitor
nuclear factor erythroid derived, like (NRF2) activator

Cross-references

PubChem CID: 400769
ChEMBL: CHEMBL1762621
DrugBank: DB05983
ChEBI: 177406
KEGG: D09585
PDB: A1L9B
Wikipedia: Bardoxolone_methyl
TTD: D0JU5X

Synonyms

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