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EVEROLIMUS

SynDRA canonical compound SYN0028175 — structure-anchored drug synonym record

All known targets

• FKBP1A
• MTOR
• ABCB1
• CYP3A5

Mechanisms of action (all sources)

• FKBP1A INHIBITOR
• FK506-binding protein 1A inhibitor
• MTOR inhibitor

Drug classes

• Protein Kinase Inhibitors
• Antineoplastic Agents
• Enzyme Inhibitors
• Immunologic Factors
• Immunosuppressive Agents
• MTOR Inhibitors
• Kinase Inhibitor
• mTOR Inhibitors
• mTOR Inhibitor Immunosuppressant
• Cytochrome P450 2D6 Inhibitors
• Cytochrome P450 3A4 Inhibitors

ATC classes

• L01E · PROTEIN KINASE INHIBITORS
• L04A · IMMUNOSUPPRESSANTS

Cross-references

• PubChem CID: 6442177
• ChEMBL: CHEMBL1908360
• DrugBank: DB01590
• ChEBI: CHEBI:68478
• KEGG: D02714
• RxNorm: 141704
• Wikipedia: Everolimus
• TTD: D0K3QS

Synonyms

• votubia
• afinitor
• certican
• RAD001
• 40-o-(2-hydroxyethyl)-rapamycin
• 42-o-(2-hydroxyethyl)rapamycin
• Rapamycin, 42-o-(2-hydroxyethyl)-
• SDZ-RAD
• RAD-666
• RAD-001
• Afinitor
• Afinitor disperz
• Certican
• Votubia
• Zortress
• Afinitor (TN)
• CERTICAN(R)
• Certican (TN)
• Everolimus (JAN/USAN/INN)
• Everolimus [USAN]
• MTOR kinase inhibitors
• NVP-RAD-001
• RAD-001C
• RAD001, SDZ-RAD, Certican, Zortress, Afinitor, Everolimus
• 001, RAD
• 40-O-(2-hydroxyethyl)-rapamycin
• 40-O-(2-Hydroxyethyl)rapamycin
• RAD
• RAD, SDZ
• 42-O-(2-Hydroxyethyl)rapamycin
• Afinitor Disperz
• CHEBI:68478
• Rapamycin, 42-O-(2-hydroxyethyl)-
• 9HW64Q8G6G
• Everolimus (INN)
• NCGC00167512-01
• Everolimus (RAD001)
• EVEROLIMUS [INN]

Reported adverse events

• Infection
• Nephrotoxicity
• Pyrexia
• Pneumonitis
• Vomiting
• Fatigue
• Insomnia
• Angioedema
• Hypersensitivity
• Rash
• Stomatitis
• Arthralgia