← SynDRA

KW-2449

SynDRA canonical compound SYN0028187 — structure-anchored drug synonym record

All known targets

• ABL1
• FLT3
• AURKA
• AURKB
• FGFR1

Mechanisms of action (all sources)

• AURKA INHIBITOR
• Serine/threonine-protein kinase Aurora-A inhibitor
• AURKB INHIBITOR
• Serine/threonine-protein kinase Aurora-B inhibitor
• FLT3 INHIBITOR
• Tyrosine-protein kinase receptor FLT3 inhibitor
• ABL1 INHIBITOR
• Tyrosine-protein kinase ABL inhibitor
• Abl kinase inhibitor
• aurora kinase inhibitor

Cross-references

• PubChem CID: 11427553
• ChEMBL: CHEMBL1908397
• ChEBI: 91441
• TTD: D00ABO

Synonyms

• Tumor antigen-specific mAb (cancer), Kyowa
• Tumor antigen-specific monoclonal antibody (cancer), Kyowa Hakko Kirin
• Tumor antigen-specific monoclonal antibody (cancer), Kyowa Hakko Kogyo
• KW2449
• UNII-2D9N67F58G
• KW 2449 [WHO-DD]
• Piperazine, 1-(4-((1E)-2-(1H-indazol-3-yl)ethenyl)benzoyl)-
• RefChem:151583
• FLT3/ABL/AURORA KINASE INHIBITOR KW-2449
• MFCD18385006
• 2D9N67F58G
• 1-[4-[(1E)-2-(1H-Indazol-3-yl)ethenyl]benzoyl]piperazine
• 3-{2-[4-(PIPERAZINE-1-CARBONYL)PHENYL]ETHENYL}-1H-INDAZOLE
• YYLKKYCXAOBSRM-JXMROGBWSA-N
• KW-2449 Hydrochloride?
• orb15754
• MLS006011271
• GTPL5691
• SCHEMBL1596894
• SCHEMBL29356539
• CHEBI:91441
• GLXC-05879
• EX-A2306
• BDBM50355496
• NSC759675
• NSC800778
• s2158
• AKOS027460993
• CCG-267833
• CS-0231
• NSC-759675
• NSC-800778
• SDCCGSBI-0654393.P001
• NCGC00346569-05
• NCGC00346569-07
• AC-28419
• AS-71712
• FI153964