← SynDRA

APITOLISIB

SynDRA canonical compound SYN0028399 — structure-anchored drug synonym record

All known targets

• MTOR
• PIK3CG
• FGR
• MAP3K9
• PIK3CA
• PIK3CB
• PIK3CD
• SYK

Mechanisms of action (all sources)

• MTOR inhibitor
• PI3K inhibitor
• Serine/threonine-protein kinase mTOR inhibitor
• MTOR MODULATOR
• PIK3CG MODULATOR

Cross-references

• PubChem CID: 25254071
• ChEMBL: CHEMBL1922094
• DrugBank: DB12180
• KEGG: D10543
• PDB: 980
• TTD: D0O6VZ
• LINCS BRD: BRD-K23228615

Synonyms

• GNE-390
• RG-7422
• APITOLISIB (GDC-0980)
• G-038390
• G-038390.1
• GDC-0980
• GDC-0980 (RG7422)
• GDC-0980.1
• GDC-0980/RG7422
• RG7422
• GDC0980
• (S)-1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one
• UNII-1C854K1MIJ
• Apitolisib (GDC-0980, RG7422)
• 1C854K1MIJ
• CHEMBL1922094
• (2s)-1-(4-{[2-(2-Aminopyrimidin-5-Yl)-7-Methyl-4-(Morpholin-4-Yl)thieno[3,2-D]pyrimidin-6-Yl]methyl}piperazin-1-Yl)-2-Hydroxypropan-1-One
• J-502360
• C23H30N8O3S
• GDC 0980
• Gne-390
• apitolisibum
• RefChem:1077141
• DTXCID1068229
• Apitolisib [USAN:INN]
• GDC-0980 (Apitolisib)
• MFCD20274520
• Apitolisib (GDC-0980)
• GNE 390; GDC 0980; RG 7422
• APITOLISIB [INN]
• Apitolisib (USAN/INN)
• APITOLISIB [USAN]
• APITOLISIB [WHO-DD]
• Apitolisib(GDC-0980)?
• SCHEMBL466297
• GTPL7888
• orb1307117
• SCHEMBL29447291
• EX-A041