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ILORASERTIB
SynDRA canonical compound SYN0028851 — structure-anchored drug synonym record
| Clinical phase | Phase 3 |
| Primary target(s) | AURKC | KDR | VEGFA |
| Mechanism of action | aurora kinase inhibitor |
| Indication | chronic myelomonocytic leukemia (cmmol) |
| Disease area | hematologic malignancy |
All known targets
- AURKC
- AURKA
- AURKB
- KDR
- FLT1
- PDGFRB
- FLT4
- PDGFRA
- LCK
- VEGFA
- SRMS
- SRC
Mechanisms of action (all sources)
- AURKB INHIBITOR
- Serine/threonine-protein kinase Aurora inhibitor
- AURKC INHIBITOR
- AURKA INHIBITOR
- FLT1 INHIBITOR
- Vascular endothelial growth factor receptor inhibitor
- FLT4 INHIBITOR
- KDR INHIBITOR
- FYN INHIBITOR
- SRC inhibitor
- LCK INHIBITOR
- YES1 INHIBITOR
Drug classes
- Antineoplastic Agents
- Protein Kinase Inhibitors
Cross-references
Synonyms
- ABT-348
- A-968660
- A-968660.0
- ABBOTT-968660
- Abt-348, a-968660
- ABT 348
- UNII-6L5D03D975
- ABT348
- 6L5D03D975
- Abbott-969660
- Ilorasertib [USAN:INN]
- Ilorasertib (USAN)
- Kinome_405
- GTPL9914
- SCHEMBL3381224
- CHEMBL1980297
- DTXSID10153718
- WPHKIQPVPYJNAX-UHFFFAOYSA-N
- BCP07256
- ZINC63298074
- BDBM50381716
- SB16853
- CS-6804
- DB11694
- KB-74395
- HY-16018
- US8722890, 1
- Z-3287
- US8722890, 2
- D10423
- N-(4-{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridin-3-yl}phenyl)-N'-(3-fluorophenyl)urea
- ilorasertibum
- RefChem:147898
- DTXCID0076209
- Ilorasertib [USAN]
- MFCD25976780
- ILORASERTIB [INN]
- Ilorasertib (USAN/INN)
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