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BELUMOSUDIL
SynDRA canonical compound SYN0028910 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Approval status | Approved · Rx |
|---|
| Primary target(s) | ROCK2 |
|---|
| Mechanism of action | rho associated kinase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- ROCK2 INHIBITOR
- Rho-associated protein kinase 2 inhibitor
- ROCK1 INHIBITOR
- rho associated kinase inhibitor
Drug classes
- Enzyme Inhibitors
- Protein Kinase Inhibitors
ATC classes
- L04A · IMMUNOSUPPRESSANTS
Cross-references
Synonyms
- belumosudil mesylate
- rezurock
- KD025
- SLx-2119
- Rock2 inhibitor kd025
- Slx-2119 free base
- KD-025
- SLx 2119
- KD 025
- ROCK inhibitor 2
- 2-(3-(4-((1H-indazol-5-yl)amino)quinazolin-2-yl)phenoxy)-N-isopropylacetamide
- Rezurock
- Belumosudil [USAN]
- 2-[3-[4-(1H-indazol-5-ylamino)quinazolin-2-yl]phenoxy]-N-propan-2-ylacetamide
- SLx2119
- 834YJF89WO
- C26H24N6O2
- KD025 (SLx-2119)
- SLx-2119(KD-025)
- Acetamide, 2-(3-(4-(1H-indazol-5-ylamino)-2-quinazolinyl)phenoxy)-N-(1-methylethyl)-
- 2-(3-(4-(1H-indazol-5-ylamino)quinazolin-2-yl)phenoxy)-N-isopropylacetamide
- 2-[3-[4-(1~{H}-indazol-5-ylamino)quinazolin-2-yl]phenoxy]-~{N}-propan-2-yl-ethanamide
- 2-[3-[4-(1H-indazol-5-ylamino)-2-quinazolinyl]phenoxy]-N-(1-methylethyl)-acetamide
- 2-[3-[4-[(1H-Indazol-5-yl)amino]quinazolin-2-yl]phenoxy]-N-isopropylacetamide
- UNII-834YJF89WO
- Kinome_2597
- BELUMOSUDIL [INN]
- BELUMOSUDIL [WHO-DD]
- SCHEMBL878202
- GTPL9558
- CHEMBL2005186
- DTXSID80238425
- BDBM322155
- BDBM435505
- BCP15921
- EX-A2314
- MFCD23098791
- s7936
Reported adverse events
- Abdominal pain
- Arthralgia
- Asthenia
- Clostridium difficile colitis
- Cough
- Dysphagia
- Epstein-Barr virus infection
- Headache
- Hypertension
- Infection
- Musculoskeletal pain
- Nasal congestion
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