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IVACAFTOR
SynDRA canonical compound SYN0028930 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx |
|---|
| Primary target(s) | CFTR |
|---|
| Mechanism of action | CFTR channel potentiator |
|---|
| Indication | cystic fibrosis |
|---|
| Disease area | pulmonary |
|---|
All known targets
Mechanisms of action (all sources)
- CFTR channel potentiator
- CFTR POSITIVE MODULATOR
- Cystic fibrosis transmembrane conductance regulator positive modulator
- CFTR POTENTIATION
- CFTR MODULATOR
Drug classes
- Chloride Channel Agonists
- Membrane Transport Modulators
- Chloride Channel Activation Potentiators
- Cystic Fibrosis Transmembrane Conductance Regulator Potentiator
- P-Glycoprotein Inhibitors
- Cytochrome P450 2C9 Inhibitors
- Cytochrome P450 3A Inhibitors
ATC classes
- R07A · OTHER RESPIRATORY SYSTEM PRODUCTS
Cross-references
Synonyms
- kalydeco
- VX 770
- VX-770
- Ivacaftor component of orkambi
- Ivacaftor component of symkevi
- Ivacaftor component of trikafta
- Kalydeco
- Kalydeco (TN)
- ORKAMBI COMPONENT IVACAFTOR
- 1Y740ILL1Z
- SYMKEVI COMPONENT IVACAFTOR
- TRIKAFTA COMPONENT IVACAFTOR
- ivacaftorum
- CHEBI:66901
- RefChem:58494
- DTXCID00158772
- R07AX02
- Elexacaftor, Tezacaftor, and Ivacaftor
- Ivacaftor (VX-770)
- Ivacaftor-d18
- MFCD17171361
- s1144
- Ivacaftor (4-tertbutyl-d9) (Major)
- Ivacaftor [USAN]
- Ivacaftor [USAN:INN]
- UNII-1Y740ILL1Z
- VX7
- IVACAFTOR [INN]
- IVACAFTOR [MI]
- Ivacaftor (USAN/INN)
- IVACAFTOR [VANDF]
- IVACAFTOR [WHO-DD]
- MLS006011119
- SCHEMBL351373
- SCHEMBL417309
- GTPL4342
- orb1305294
- IVACAFTOR [ORANGE BOOK]
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