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GLASDEGIB
SynDRA canonical compound SYN0029362 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx |
|---|
| Primary target(s) | DHH | IHH | SMO |
|---|
| Mechanism of action | hedgehog pathway inhibitor |
|---|
| Indication | acute myeloid leukemia (AML) |
|---|
| Disease area | hematologic malignancy |
|---|
All known targets
Mechanisms of action (all sources)
- SMO ANTAGONIST
- Smoothened homolog antagonist
- hedgehog pathway inhibitor
- SMO MODULATOR
- MTOR INHIBITOR
Drug classes
- Smoothened Receptor Antagonists
- Hedgehog Pathway Inhibitor
ATC classes
- L01X · OTHER ANTINEOPLASTIC AGENTS
Cross-references
Synonyms
- daurismo
- PF-04449913
- PF-4449913
- PF 04449913
- UNII-K673DMO5H9
- K673DMO5H9
- CHEMBL2043437
- Glasdegib (PF-04449913)
- Glasdegib [USAN:INN]
- Glasdegib (USAN/INN)
- PF-04449913;Glasdegib
- GTPL8201
- Glasdegib(PF-04449913)
- EX-A858
- MolPort-035-789-706
- SFNSLLSYNZWZQG-VQIMIIECSA-N
- ZINC68251434
- PF-913
- BDBM50385635
- 2640AH
- AKOS027324121
- CS-2
- glasdegibum
- CHEBI:145428
- RefChem:57731
- L01XX63
- DTXCID801510133
- PF04449913
- C21H22N6O
- MFCD25976839
- GLASDEGIB [INN]
- GLASDEGIB [MI]
- GLASDEGIB [USAN]
- GLASDEGIB [WHO-DD]
- orb1300702
- SCHEMBL2068480
- SCHEMBL29359708
- Glasdegib(PF-04449913)?
Reported adverse events
- Abdominal pain
- Constipation
- Dysgeusia
- Fatigue
- Febrile neutropenia
- Muscle spasms
- Nausea
- Platelet count decreased
- Pneumonia
- Pyrexia
- Rash
- Thrombocytopenia
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