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LEVOSIMENDAN

SynDRA canonical compound SYN0029468 — structure-anchored drug synonym record

All known targets

• TNNC1
• PDE3A
• KCNJ11
• KCNJ8
• PDE3B
• TNNI3
• TNNT2

Mechanisms of action (all sources)

• Calcium sensitizer
• PDE3A INHIBITOR
• Phosphodiesterase 3 inhibitor
• PDE3B INHIBITOR
• TNNC1 POSITIVE MODULATOR
• Troponin, cardiac muscle positive modulator
• TNNI3 POSITIVE MODULATOR
• TNNT2 POSITIVE MODULATOR
• TNNC1 STIMULATOR
• TNNC1 OPENER

Drug classes

• Cardiotonic Agents
• Cardiovascular Agents
• Enzyme Inhibitors
• Phosphodiesterase 3 Inhibitors
• Phosphodiesterase Inhibitors
• Protective Agents
• Vasodilator Agents

ATC classes

• C01C · CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES

Cross-references

• PubChem CID: 3033825
• ChEMBL: CHEMBL2051955
• DrugBank: DB00922
• ChEBI: CHEBI:50567
• KEGG: D04720
• Wikipedia: Levosimendan
• TTD: D0C4HG
• LINCS BRD: BRD-K03095347

Synonyms

• (R)-Simendan
• simdax
• (r)-simendan
• Simendan, (r)-
• (-)-OR-1259
• NSC-759644
• OR-1259
• OR1259
• Simdax
• Levosimedan
• Levosimendanum
• Levosimendan [INN]
• Simdax (TN)
• Levosimendan (USAN/INN)
• Mesoxalonitrile(p-((R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-pyridazinyl)phenyl)hydrazone
• Mesoxalonitrile (-)-(p((R)-1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazone
• ((4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazono)propanedinitrile
• (R)-((4-(1,4,5,6-Tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazono) propanedintrile
• (R)-((4-(1,4,5,6-Tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazono)propanedinitrile
• ({4-[(4R)-4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl]phenyl}hydrazono)propanedintrile
• 2-[[4-[(4R)-4-methyl-6-oxo-4,5-dihydro-1H-pyridazin-3-yl]phenyl]hydrazinylidene]propanedinitrile
• levosimendanum
• OR 1259
• NSC 759644
• CHEBI:50567
• C6T4514L4E
• DTXCID7026445
• RefChem:799036
• C01CX08
• MFCD00867135
• Simsndan;OR-1259
• SMR002529692
• CAS-141505-33-1
• Levosimendan [USAN:INN]
• UNII-C6T4514L4E
• Levosimendan (Standard)
• LEVOSIMENDAN [MI]
• LEVOSIMENDAN [USAN]