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DROXIDOPA
SynDRA canonical compound SYN0030031 — structure-anchored drug synonym record
| Clinical phase | Launched |
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| Approval status | Approved · Rx/OTC |
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| Primary target(s) | ADRB3 |
|---|
| Mechanism of action | Norepinephrine precursor |
|---|
| Indication | hypertension | Parkinson's Disease |
|---|
| Disease area | cardiology | neurology/psychiatry |
|---|
All known targets
- ADRA1A
- ADRA1B
- ADRA1D
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- ADRB3
- CHRM1
- PAH
Mechanisms of action (all sources)
- Norepinephrine precursor
- ADRA1A AGONIST
- Adrenergic receptor agonist
- ADRA2A AGONIST
- ADRB1 AGONIST
- ADRB2 AGONIST
- ADRA2C AGONIST
- ADRA1D AGONIST
- ADRA1B AGONIST
- ADRA2B AGONIST
- ADRB3 AGONIST
Drug classes
- Catecholamine
- Adrenergic Agents
- Adrenergic Agonists
- Adrenergic alpha-Agonists
- Cardiovascular Agents
- Neurotransmitter Agents
- Peripheral Nervous System Agents
- Sympathomimetics
- Vasoconstrictor Agents
- Anti-Dyskinesia Agents
- Antiparkinson Agents
- Central Nervous System Agents
ATC classes
- C01C · CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
Cross-references
Synonyms
- northera
- L-DOPS
- threo-Dopaserine
- L-threo-3,4-Dihydroxyphenylserine
- L-threo-dops
- DOPS
- Northera
- (2S,3R)-2-amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid
- DL-threo-DOPS
- L-Threodops
- DL-threo-3,4-Dihydroxyphenylserine
- DL-threo-Droxidopa
- DL-threo-Dihydroxyphenylserine
- UNII-J7A92W69L7
- SM 5688
- CHEBI:31524
- Droxidopa (L-DOPS)
- threo-beta,3-Dihydroxy-DL-tyrosine
- EINECS 223-480-5
- beta,3-Dihydroxy-DL-tyrosine threo-
- BRN 2852792
- L-threo-dihydroxyphenylserine
- DL-threo-3-(3,4-Dihydroxyphenyl)serine
- Serine, 3-(3,4-dihydroxyphenyl)-, DL-threo-
- J7A92W69L7
- L-Tyrosine, beta,3-dihydroxy-, (betaR)-
- L-threo DOPS
- THREO-3,4-DIHYDROXYPHENYLSERINE, L-
- L-dihydroxyphenylserine
- droxidopum
- SM-5688
- L-Tyrosine, beta,3-dihydroxy-, threo-
- threo-DOPS
- 3,4-threo-DOPS
- 3,4-Dihydroxyphenylserine
- erythro 3,4 Dihydroxyphenylserine
- RefChem:56670
- C01CA27
Reported adverse events
- Cerebrovascular accident
- Chest pain
- Dizziness
- Fatigue
- Headache
- Hyperpyrexia
- Hypertension
- Nausea
- Pancreatitis
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