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LUMACAFTOR
SynDRA canonical compound SYN0030068 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx |
|---|
| Primary target(s) | CFTR |
|---|
| Mechanism of action | CFTR channel agonist |
|---|
| Indication | cystic fibrosis |
|---|
| Disease area | pulmonary |
|---|
All known targets
Mechanisms of action (all sources)
- CFTR STABILISER
- Cystic fibrosis transmembrane conductance regulator stabiliser
- CFTR BINDER
- CFTR channel agonist
- CFTR REGULATOR
- CFTR PHARMACOLOGICAL CHAPERONE
Drug classes
- P-Glycoprotein Inhibitors
- Cytochrome P450 2C9 Inhibitors
- Cytochrome P450 2C9 Inducers
- Cytochrome P450 2C19 Inducers
- Cytochrome P450 2C8 Inhibitors
- Cytochrome P450 2C8 Inducers
- Cytochrome P450 2B6 Inducers
- Cytochrome P450 3A Inducers
- P-Glycoprotein Inducers
ATC classes
- OTHER RESPIRATORY SYSTEM PRODUCTS
Cross-references
Synonyms
- VX-809
- VRT-826809
- VRT826809
- VX809
- Lumacaftor component of orkambi
- VRT-325
- VRT-422
- VRT-532
- VX 809
- VRT 826809
- EGP8L81APK
- CHEBI:90951
- ORKAMBI COMPONENT LUMACAFTOR
- lumacaftorum
- RefChem:154271
- DTXCID80162014
- VX-809 (Lumacaftor)
- MFCD16659051
- Lumacaftor [INN]
- Lumacaftor [USAN:INN]
- UNII-EGP8L81APK
- C24H18F2N2O5
- VX8
- LUMACAFTOR [MI]
- Lumacaftor (USAN/INN)
- Lumacaftor (VX-809)
- LUMACAFTOR [USAN]
- LUMACAFTOR [WHO-DD]
- Lumacaftor(vx-809vx809)
- MLS006011120
- SCHEMBL377028
- Lumacaftor(vx-809vx809)?
- GTPL7481
- orb1305285
- LUMACAFTOR [ORANGE BOOK]
- SCHEMBL29355737
- SCHEMBL29355738
- SCHEMBL29370751
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