← SynDRA

MACITENTAN

SynDRA canonical compound SYN0030071 — structure-anchored drug synonym record

All known targets

• EDNRA
• EDNRB

Mechanisms of action (all sources)

• Endothelin receptor antagonist
• EDNRB ANTAGONIST
• Endothelin receptor, ET-A/ET-B antagonist
• EDNRA ANTAGONIST
• EDNRA MODULATOR
• EDNRB MODULATOR

Drug classes

• Endothelin Receptor Antagonists
• Endothelin Receptor Antagonist
• Endothelin A Receptor Antagonists
• Endothelin B Receptor Antagonists

ATC classes

• C02K · OTHER ANTIHYPERTENSIVES

Cross-references

• PubChem CID: 16004692
• ChEMBL: CHEMBL2103873
• DrugBank: DB08932
• ChEBI: CHEBI:76607
• KEGG: D10135
• RxNorm: 1442132
• PDB: A1D5I
• Wikipedia: Macitentan
• TTD: D0S7JH
• LINCS BRD: BRD-K48812570

Synonyms

• opsumit
• ACT-064992
• Macitentan component of opsynvi
• Opsumit
• ACT 064992
• UNII-Z9K9Y9WMVL
• ACT064992
• Z9K9Y9WMVL
• N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'-propylsulfamide
• N-(5-(4-Bromophenyl)-6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-4-pyrimidinyl)-N'-propylsulfamide
• CHEBI:76607
• Actelion-1
• Macitentan [USAN:INN]
• macitentanum
• zlchem 5
• Opsumit (TN)
• Macitentan (JAN/USAN)
• (non-labelled)Macitentan-d7
• MLS006011174
• C19H20Br2N6O4S
• SCHEMBL1445625
• GTPL7352
• CHEMBL2103873
• ZLA0005
• EX-A544
• DTXSID50196063
• OPSYNVI COMPONENT MACITENTAN
• RefChem:58979
• C02KX04
• DTXCID60118554
• MFCD17167076
• Macitentan [INN]
• Macitentan (Standard)
• MACITENTAN [MI]
• MACITENTAN [JAN]
• MACITENTAN [USAN]
• MACITENTAN [VANDF]
• A1D5I

Reported adverse events

• Bronchitis
• Headache
• Influenza
• Nasopharyngitis
• Urinary tract infection
• Hepatotoxicity