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VORTIOXETINE
SynDRA canonical compound SYN0030957 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx |
|---|
| Primary target(s) | SLC6A4 |
|---|
| Mechanism of action | Serotonin receptor antagonist |
|---|
| Indication | depression |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- SLC6A4
- HTR1A
- HTR7
- HTR1B
- HTR5A
- HTR1D
- HTR6
- HTR3A
- HTR2C
- HTR2A
- Slc6a3
- Htr7
Mechanisms of action (all sources)
- Serotonin receptor agonist
- Serotonin receptor antagonist
- HTR1A AGONIST
- Serotonin 1a (5-HT1a) receptor agonist
- SLC6A4 INHIBITOR
- Serotonin transporter inhibitor
- HTR3A ANTAGONIST
- Serotonin 3a (5-HT3a) receptor antagonist
- HTR1A PARTIAL AGONIST
- HTR1B PARTIAL AGONIST
- HTR3A|HTR3B PARTIAL AGONIST
- HTR5A ANTAGONIST
Drug classes
- Anti-Anxiety Agents
- Antidepressive Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Membrane Transport Modulators
- Neurotransmitter Agents
- Neurotransmitter Uptake Inhibitors
- Psychotropic Drugs
- Selective Serotonin Reuptake Inhibitors
- Serotonin 5-HT1 Receptor Agonists
- Serotonin 5-HT3 Receptor Antagonists
- Serotonin Agents
ATC classes
Cross-references
Synonyms
- vortioxetine DL-lactate
- brintellix
- Lu AA21004
- vortioxetine hydrobromide
- Vortioxetina
- LU-AA21004
- LUAA21004
- Brintellix
- 1-(2-((2,4-Dimethylphenyl)thio)phenyl)piperazine
- Lu-AA21004
- UNII-3O2K1S3WQV
- 3O2K1S3WQV
- CHEBI:76016
- Trintellix
- 1-{2-[(2,4-dimethylphenyl)sulfanyl]phenyl}piperazine
- Piperazine, 1-[2-[(2,4-dimethylphenyl)thio]phenyl]-
- Brintellix (TN)
- 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine
- 1-[2-(2,4-dimethylphenyl)sulfanylphenyl]piperazine
- 1-[2-(2,4-dimethyl-phenylsulfanyl)-phenyl]-piperazine
- CHEMBL2204360
- 1-[2-[(2,4-Dimethylphenyl)thio]phenyl]piperazine
- LuAA21004
- Piperazine, 1-(2-((2,4-dimethylphenyl)thio)phenyl)-
- 1-(2-((2,4-DIMETHYLPHENYL)SULFANYL)PHENYL)PIPERAZINE
- vortioxetina
- vortioxetinum
- 1-(2-(2,4-dimethylphenylsulfanyl)phenyl)piperazine
- 1-(2-((2,4-Dimethylphenyl)sulfanyl)phenyl}piperazine
- RefChem:57757
- N06AX26
- DTXCID801392739
- Vortioxetine free base
- Vortioxetine [USAN]
- C18H22N2S
- Vortioxetine (USAN)
- Vortioxetine [USAN:INN]
- VTX
Reported adverse events
- Abnormal dreams
- Constipation
- Dizziness
- Nausea
- Pruritus
- Sexual dysfunction
- Vomiting
- Dry mouth
- Flatulence
- Hypersensitivity
- Hypomania
- Mania
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