← SynDRA
TELOTRISTAT ETHYL
SynDRA canonical compound SYN0031563 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx |
|---|
| Primary target(s) | TPH1 |
|---|
| Mechanism of action | tryptophan hydroxylase inhibitor |
|---|
| Indication | diarrhea |
|---|
| Disease area | gastroenterology |
|---|
All known targets
Mechanisms of action (all sources)
- TPH2 INHIBITOR
- Tryptophan 5-hydroxylase inhibitor
- TPH1 INHIBITOR
- tryptophan hydroxylase inhibitor
- Modulator
Cross-references
Synonyms
- xermelo
- telotristat etiprate
- LX1606
- LX 1606
- LX-1032
- LX-1606
- LX1032
- Xermelo
- Telotristat
- Telotristat etiprate
- LP-778902
- Serotonin modulator (oral, GI disorder/hypertension/carcinoid syndrome), Lexicon
- Tryptophan hydroxylase inhibitor (oral, GI disorder/hypertension/carcinoid syndrome), Lexicon
- telotristat.ethyl
- (S)-Ethyl 2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoate
- Telotristat ethyl [USAN]
- ethyl (2S)-2-amino-3-[4-[2-amino-6-[(1R)-1-[4-chloro-2-(3-methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyrimidin-4-yl]phenyl]propanoate
- 8G388563M7
- Telotristat ethyl (USAN)
- LX-1606 Hippurate
- Telotristat Etiprate (LX 1606 Hippurate)
- UNII-8G388563M7
- Xermelo (TN)
- SCHEMBL610588
- TELOTRISTAT ETHYL [MI]
- GTPL9490
- CHEMBL2105695
- EX-A322
- BDBM445704
- DTXSID001102271
- TELOTRISTAT ETHYL [WHO-DD]
- AMY38688
- HY-13055A
- LX1606LX1606
- MFCD18251583
- ZINC43205655
- BCP9000866
- DB12095
Reported adverse events
- Depression
- Flatulence
- Headache
- Decreased appetite
- Nausea
- Pyrexia
Look up TELOTRISTAT ETHYL in the interactive SynDRA portal →