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CABOZANTINIB

SynDRA canonical compound SYN0031584 — structure-anchored drug synonym record

All known targets

• KDR
• MET
• RET
• TEK
• FLT3
• KIT
• SRC
• RIPK3
• RIPK2
• PTK6
• PIP4K2C
• NTRK1

Mechanisms of action (all sources)

• VEGFR inhibitor
• RET tyrosine kinase inhibitor
• KDR INHIBITOR
• Vascular endothelial growth factor receptor 2 inhibitor
• MET INHIBITOR
• Hepatocyte growth factor receptor inhibitor
• RET INHIBITOR
• KIT INHIBITOR
• FLT3 INHIBITOR
• TEK INHIBITOR

Drug classes

• Protein Kinase Inhibitors
• Kinase Inhibitor

ATC classes

• L01E · PROTEIN KINASE INHIBITORS

Cross-references

• PubChem CID: 25102847
• ChEMBL: CHEMBL2105717
• DrugBank: DB08875
• ChEBI: CHEBI:72319
• KEGG: D10062
• RxNorm: 1363268
• Wikipedia: Cabozantinib
• TTD: D0IQ6P
• LINCS BRD: BRD-K51544265

Synonyms

• cabozantinib malate
• cabozantinib (S)-malate
• cometriq
• XL184
• cabozantinib S-malate
• cabometyx
• BMS-907351
• BMS-907351 FREE BASE
• Cabometyx
• CABOZANTINIB (BMS-907351)
• Cabozantinib s-malate
• CABOZANTINIBCT-XL184COMETRIQXL184C3627
• Cometriq
• XL-184
• XL-184 FREE BASE
• XL184 FREE BASE
• XL184,BMS-907351
• XL 184
• BMS 907351
• XL-184 free base
• Cabozantinib (XL184, BMS-907351)
• Cabozantinib [USAN]
• CHEBI:72317
• BMS907351
• 1C39JW444G
• MFCD20926324
• Cabozantinib (USAN)
• N'-[4-[(6,7-DIMETHOXY-4-QUINOLINYL)OXY]PHENYL]-N-(4-FLUOROPHENYL)-1,1-CYCLOPROPANEDICARBOXAMIDE
• XL-184 (Cabozantinib,BMS907351)
• Cabometyx (TN)
• Cometriq (TN)
• 1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
• n-(4-((6,7-dimethoxy-4-quinolinyl)oxy)phenyl)-n'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide
• 1,1-Cyclopropanedicarboxamide, N'-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-
• N-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N'-(4-fluorophenyl)cyclopropane-1,1- dicarboxamide
• XL184 cpd
• Cabozantinib [USAN:INN]
• Carbozantinib