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SONIDEGIB
SynDRA canonical compound SYN0031598 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · Rx |
| Primary target(s) | SMO |
| Mechanism of action | Smoothened receptor antagonist |
| Indication | basal cell carcinoma (BCC) |
| Disease area | oncology |
All known targets
Mechanisms of action (all sources)
- Smoothened receptor antagonist
- SMO inhibitor
- Smoothened homolog inhibitor
- SMO MODULATOR
- SMO ANTAGONIST
Drug classes
- Smoothened Receptor Antagonists
- Hedgehog Pathway Inhibitor
ATC classes
- L01X · OTHER ANTINEOPLASTIC AGENTS
Cross-references
Synonyms
- sonidegib diphosphate
- odomzo
- LDE225
- erismodegib
- LDE-225
- NPV-LDE-225
- sonidegib phosphate
- NVP-LDE-225
- NVP-LDE225
- Erismodegib
- Odomzo
- LDE 225
- Sonidegib (LDE-225)
- LDE225 (NVP-LDE225,Erismodegib)
- 0RLU3VTK5M
- LDE225 Diphosphate
- 956697-53-3 (free base)
- N-(6-((2S,6R)-2,6-dimethylmorpholino)pyridin-3-yl)-2-methyl-4'-(trifluoromethoxy)biphenyl-3-carboxamide
- N-(6-((cis-2,6-Dimethylmorpholin-4-yl)-3-pyridyl)-2-methyl-3-(4-(trifluoromethoxy)phenyl)benzamide
- Odomozo
- N-(6-((2R,6S)-2,6-dimethylmorpholino)pyridin-3-yl)-2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carboxamide
- n-(6-((2r,6s)-2,6-dimethylmorpholino)pyridin-3-yl)-2-methyl-4'-(trifluoromethoxy)biphenyl-3-carboxamide
- N-[6-(cis-2,6-dimethylmorpholin-4-yl)pyridin-3-yl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide
- N-[6-[(2S,6R)-2,6-dimethylmorpholin-4-yl]pyridin-3-yl]-2-methyl-3-[4-(trifluoromethoxy)phenyl]benzamide
- Sonidegib [USAN:INN]
- UNII-0RLU3VTK5M
- Erismodegib [USAN:INN]
- Sonidegib phospate
- (1,1'-Biphenyl)-3-carboxamide, N-(6-((2R,6S)-2,6-dimethyl-4-morpholinyl)-3-pyridinyl)-2- methyl-4'-(trifluoromethoxy)-, rel-
- [1,1'-Biphenyl]-3-carboxamide, N-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)-, rel-
- LDE225 (NVP-LDE225; Erismodegib)
- SONIDEGIB [INN]
- SONIDEGIB [MI]
- Sonidegib (USAN/INN)
- SONIDEGIB [USAN]
- erismodegib (deleted INN)
- SONIDEGIB [WHO-DD]
- NVP-LDE225(Erismodegib)
Reported adverse events
- Abdominal pain
- Alopecia
- Dysgeusia
- Fatigue
- Headache
- Muscle spasms
- Musculoskeletal pain
- Myalgia
- Nausea
- Pruritus
- Vomiting
- Decreased appetite
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