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NALDEMEDINE
SynDRA canonical compound SYN0031614 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx |
|---|
| Primary target(s) | OPRD1 | OPRK1 | OPRM1 |
|---|
| Mechanism of action | opioid receptor antagonist |
|---|
| Indication | constipation |
|---|
| Disease area | gastroenterology |
|---|
All known targets
Mechanisms of action (all sources)
- OPRM1 ANTAGONIST
- Mu opioid receptor antagonist
- opioid receptor antagonist
Drug classes
- Opioid Antagonists
- Opioid Antagonist
ATC classes
- A06A · DRUGS FOR CONSTIPATION
Cross-references
Synonyms
- symproic
- nalmedine
- naldemedine tosylate
- S-297995
- naldemedine tosilate
- Naldemedina
- S 297995
- UNII-03KSI6WLXH
- 03KSI6WLXH
- S-297,995
- Naldemedine [USAN:INN]
- Naldemedine (USAN/INN)
- SCHEMBL9880572
- GTPL9150
- CHEMBL2105755
- AKOS032945757
- DB11691
- Morphinan-7-carboxamide, 17-(cyclopropylmethyl)-6,7-didehydro-4,5-epoxy-3,6,14- trihydroxy-N-(1-methyl-1-(3-phenyl-1,2,4-oxadiazol-5-yl)ethyl)-,(5alpha)-
- J3.573.009E
- D10188
- naldemedina
- naldemedinum
- RefChem:57227
- A06AH05
- DTXCID601515444
- Naldemedine [USAN]
- NALDEMEDINE [MI]
- NALDEMEDINE [INN]
- NALDEMEDINE [WHO-DD]
- orb1695970
- SCHEMBL29376271
- EX-A10201A
- BDBM50503604
- EBC-27332
- compound 9k [PMID: 30446313]
- DA-67333
- HY-19627
Reported adverse events
- Abdominal pain
- Gastrointestinal perforation
- Nausea
- Vomiting
- Gastroenteritis
- Gastrointestinal disorder
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