← SynDRA

BARICITINIB

SynDRA canonical compound SYN0031618 — structure-anchored drug synonym record

All known targets

• JAK2
• JAK1
• AAK1
• GAK
• TYK2
• BMP2K
• JAK3
• PRKCA
• PRKCB
• PRKCD
• PKN2
• RET

Mechanisms of action (all sources)

• JAK inhibitor
• JAK1 INHIBITOR
• Tyrosine-protein kinase JAK1 inhibitor
• JAK2 INHIBITOR
• Tyrosine-protein kinase JAK2 inhibitor
• AAK1 INHIBITOR
• BMP2K INHIBITOR
• GAK INHIBITOR
• JAK3 INHIBITOR
• TYK2 INHIBITOR
• JAK2 MODULATOR
• JAK1 MODULATOR

Drug classes

• Janus Kinase Inhibitors
• Janus Kinase Inhibitor

ATC classes

• L04A · IMMUNOSUPPRESSANTS

Cross-references

• PubChem CID: 44205240
• ChEMBL: CHEMBL2105759
• DrugBank: DB11817
• ChEBI: CHEBI:95341
• KEGG: D10308
• RxNorm: 2047232
• PDB: 3JW
• Wikipedia: Baricitinib
• TTD: D0Y7IC
• LINCS BRD: BRD-K53581288

Synonyms

• LY3009104
• INCB028050
• olumiant
• BARICITINIB PHOSPHATE
• BARICITINIB PHOSPHATE SALT
• INCB-28050
• 3JW
• BARICITINIB (INCB028050)
• BARICITINIB (LY3009104)
• INCB-028050
• LY-3009104
• Olumiant
• Baricitinib (LY3009104, INCB028050)
• Baricitinib [USAN:INN]
• C16H17N7O2S
• ISP4442I3Y
• J-503551
• Olumiant (TN)
• UNII-ISP4442I3Y
• 2-(3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile
• LY 3009104
• 1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile
• 2-[1-ETHYLSULFONYL-3-[4-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)PYRAZOL-1-YL]AZETIDIN-3-YL]ACETONITRILE
• 3-Azetidineacetonitrile, 1-(ethylsulfonyl)-3-(4-(7H-pyrrolo(2,3-d)pyrimidin-4-yl)-1H-pyrazol-1-yl)-
• LY3009104 (phosphate);INCB028050 (phosphate)
• INCB28050
• Baricitinib [USAN]
• INCB 28050
• 3-AZETIDINEACETONITRILE, 1-(ETHYLSULFONYL)-3-[4-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)-1H-PYRAZOL-1-YL]-
• BARICITINIB [MI]
• BARICITINIB [INN]
• BARICITINIB [JAN]
• BARICITINIB [WHO-DD]
• MLS006011247
• SCHEMBL871150
• Baricitinib (JAN/USAN/INN)
• Baricitinib (LY3009104)
• BARICITINIB [EMA EPAR]

Reported adverse events

• Lymphoma
• TB
• Thrombosis
• Active tuberculosis
• Acne
• Folliculitis
• Headache
• Infection
• Nausea
• Thrombocytosis
• Abdominal pain
• Alopecia