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BREXPIPRAZOLE
SynDRA canonical compound SYN0031619 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | HTR2A |
|---|
| Mechanism of action | Dopamine receptor partial agonist |
|---|
| Indication | depression | schizophrenia |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- DRD2
- HTR1A
- HTR2A
- DRD3
- ADRA1A
- HTR1B
- SLC6A3
- SLC6A2
- Htr2a
- Htr1a
- HTR7
- HTR6
Mechanisms of action (all sources)
- Dopamine receptor partial agonist
- DRD2 PARTIAL AGONIST
- Dopamine D2 receptor partial agonist
- HTR1A PARTIAL AGONIST
- Serotonin 1a (5-HT1a) receptor partial agonist
- HTR2A ANTAGONIST
- Serotonin 2a (5-HT2a) receptor antagonist
- HTR1A MODULATOR
- DRD2 MODULATOR
- DRD2 AGONIST
- HTR1A AGONIST
Drug classes
- Dopamine Agents
- Dopamine Agonists
- Neurotransmitter Agents
- Serotonin Agents
- Atypical Antipsychotic
ATC classes
Cross-references
Synonyms
- rexulti
- OPC 34712
- Brexpiprazol
- OPC-34712
- Rexulti
- Rxulti
- 2J3YBM1K8C
- brexpiprazol
- brexpiprazolum
- RefChem:58868
- DTXCID90161018
- N05AX16
- MFCD27987920
- C25H27N3O2S
- Brexpiprazole Impurity 141
- Brexpiprazole [USAN]
- UNII-2J3YBM1K8C
- Brexpiprazole [USAN:INN]
- Rexulti (TN)
- PS33 - Brexpiprazole
- Brexpiprazole (Standard)
- BREXPIPRAZOLE [MI]
- BREXPIPRAZOLE [INN]
- BREXPIPRAZOLE [JAN]
- Brexpiprazole(OPC34712)
- Brexpiprazole(OPC34712)?
- Brexpiprazole; OPC-34712
- BREXPIPRAZOLE [WHO-DD]
- GTPL7672
- orb1305739
- orb3141363
- SCHEMBL1037592
- Brexpiprazole (JAN/USAN/INN)
- SCHEMBL14772509
- SCHEMBL27959775
- SCHEMBL29350574
- SCHEMBL29870341
- CHEBI:134716
Reported adverse events
- Agranulocytosis
- Akathisia
- Anxiety
- Constipation
- Dizziness
- Dyskinesia
- Dyspepsia
- Dysphagia
- Dystonia
- Fall
- Fatigue
- Flatulence
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