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DIMETHYL FUMARATE

SynDRA canonical compound SYN0032880 — structure-anchored drug synonym record

All known targets

• KEAP1
• HCAR2
• NFE2L2

Mechanisms of action (all sources)

• KEAP1 INHIBITOR
• Kelch-like ECH-associated protein 1 inhibitor
• nuclear factor erythroid derived, like (NRF2) activator

Drug classes

• Dermatologic Agents
• Immunologic Factors
• Immunosuppressive Agents
• Radiation-Sensitizing Agents

ATC classes

• L04A · IMMUNOSUPPRESSANTS

Cross-references

• PubChem CID: 637568
• ChEMBL: CHEMBL2107333
• DrugBank: DB08908
• ChEBI: CHEBI:76004
• KEGG: D03846
• RxNorm: 1373478
• PDB: EOU
• Wikipedia: Dimethyl_fumarate
• TTD: D0A7MY

Synonyms

• tecfidera
• methyl fumarate
• boletic acid dimethyl ester
• BG-12
• Dimethyl fumar
• Fumaric acid dimethyl ester
• LAS41008
• Panaclar
• AZL 0 211089
• AZL-O-211089
• AZL-0211089
• BG-00012
• BG00012
• FAG-201
• FP-187
• FP187
• LAS-41008
• NSC-167432
• NSC-25942
• Dimethyl fumarate accord
• Dimethyl fumarate mylan
• Dimethyl fumarate neuraxpharm
• Dimethyl fumarate polpharma
• Dimethyl fumarate teva
• Skilarence
• Tecfidera
• TECFIDERA
• Fumaric acid-dimethyl ester
• FAG 201
• NSC 25942
• 2-butenedioic acid, (2E)-, dimethyl ester
• BG 12
• BG 00012
• AZL O 211089
• NSC 167432
• dimethyl (2E)-but-2-enedioate

Reported adverse events

• Dyspepsia
• Erythema
• Flushing
• Lymphopenia
• Nausea
• Progressive multifocal leukoencephalopathy
• Pruritus
• Vomiting
• Angioedema
• Herpes zoster
• Rash
• Abdominal pain