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EMPAGLIFLOZIN

SynDRA canonical compound SYN0033274 — structure-anchored drug synonym record

All known targets

• SLC5A2
• SLC5A1
• SLC5A10
• SLC5A11
• SLC5A9

Mechanisms of action (all sources)

• Sodium/glucose cotransporter inhibitor
• SLC5A2 INHIBITOR
• Sodium/glucose cotransporter 2 inhibitor
• SLC5A2 MODULATOR

Drug classes

• Hypoglycemic Agents
• Sodium-Glucose Transporter 2 Inhibitors
• Sodium-Glucose Cotransporter 2 Inhibitor

ATC classes

• A10B · BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS

Cross-references

• PubChem CID: 11949646
• ChEMBL: CHEMBL2107830
• DrugBank: DB09038
• ChEBI: CHEBI:82720
• KEGG: D10459
• RxNorm: 1545653
• PDB: 7R3
• Wikipedia: Empagliflozin
• TTD: D06ALD
• LINCS BRD: BRD-K53765467

Synonyms

• BI 10773
• jardiance
• Empagliflozine
• Empagliflozina
• Bi10773
• Bi 10773
• Empagliflozin component of glyxambi
• Empagliflozin component of synjardy
• Empagliflozin component of trijardy xr
• Jardiance
• JARDIANCE
• BI-10773
• UNII-HDC1R2M35U
• Empagliflozin (BI 10773)
• BI10773
• HDC1R2M35U
• CHEBI:82720
• 1-chloro-4-(glucopyranos-1-yl)-2-(4-(tetrahydrofuran-3-yloxy)benzyl)benzene
• AK160980
• (1S)-1,5-anhydro-1-(4-chloro-3-{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}phenyl)-D-glucitol
• (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
• TRIJARDY XR COMPONENT EMPAGLIFLOZIN
• GLYXAMBI COMPONENT EMPAGLIFLOZIN
• Empagliflozinum
• RefChem:5790
• A10BK03
• DTXCID901510350
• MFCD22566222
• C23H27ClO7
• Empagliflozin [INN]
• Empagliflozin [USAN:INN]
• Jardiance (TN)
• 7R3
• Empagliflozin (Standard)
• EMPAGLIFLOZIN [MI]
• BI-10773;Empagliflozin
• EMPAGLIFLOZIN [JAN]
• EMPAGLIFLOZIN [USAN]

Reported adverse events

• Angioedema
• Constipation
• Thirst
• Urinary tract infection
• Hypersensitivity
• Arthralgia
• Fournier's gangrene
• Ketoacidosis
• Nausea
• Phimosis
• Pyelonephritis
• Upper respiratory tract infection