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IXAZOMIB

SynDRA canonical compound SYN0033799 — structure-anchored drug synonym record

All known targets

• PSMB1
• PSMB5
• PSMB2
• PSMD13
• PSMC4
• PSMC5
• PSMC6
• PSMD1
• PSMD11
• PSMD12
• ADRM1
• PSMC2

Mechanisms of action (all sources)

• proteasome inhibitor
• PSMD1 INHIBITOR
• PSMB2 INHIBITOR
• PSMB1 INHIBITOR
• PSMB5 INHIBITOR
• PSMB8 INHIBITOR
• PSMB9 INHIBITOR
• PSMB6 INHIBITOR
• PSMD14 INHIBITOR
• PSMA1 INHIBITOR
• PSMA2 INHIBITOR
• PSMA3 INHIBITOR

Drug classes

• Proteasome Inhibitors
• Antineoplastic Agents
• Enzyme Inhibitors
• Protease Inhibitors
• Proteasome Inhibitor

ATC classes

• L01X · OTHER ANTINEOPLASTIC AGENTS

Cross-references

• PubChem CID: 25183872
• ChEMBL: CHEMBL2141296
• DrugBank: DB09570
• ChEBI: CHEBI:90942
• KEGG: D10130
• RxNorm: 1723735
• PDB: 6V8
• Wikipedia: Ixazomib
• LINCS BRD: BRD-K78659596

Synonyms

• ixazomib citrate
• MLN2238
• MLN9708
• ninlaro
• MLN-2238
• MLN-9708 FREE BASE
• MLN 2238
• Ixazomib [INN]
• (R)-(1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)boronic acid
• (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
• Ixazomib(MLN2238)
• Ixazomib (MLN2238)
• CHEMBL2141296
• Ixazomib (USAN)
• [(1R)-1-{2-[(2,5-dichlorophenyl)formamido]acetamido}-3-methylbutyl]boronic acid
• IXAZOMIB [USAN]
• [(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid
• Boronic acid, b-((1R)-1-((2-((2,5-dichlorobenzoyl)amino)acetyl)amino)-3-methylbutyl)-
• 71050168A2
• Ixazomib [USAN:INN]
• Ixozamib
• Ixazomib Impurity
• UNII-71050168A2
• MLN2238(Ixazomib)
• IXAZOMIB [MI]
• IXAZOMIB [WHO-DD]
• Ixazomib (MLN-2238)
• GTPL8450
• SCHEMBL3742758
• CHEBI:90942
• EX-A547
• DTXSID701025662
• AMY19380
• BCP02410
• BCP24078
• BDBM50398609
• MFCD18251438
• NSC766907

Reported adverse events

• Angioedema
• Bronchitis
• Constipation
• Eye disorder
• Herpes zoster
• Nausea
• Neutropenia
• Rash
• Thrombocytopenia
• Toxic epidermal necrolysis
• Upper respiratory tract infection
• Vomiting