← SynDRA

AFURESERTIB

SynDRA canonical compound SYN0034465 — structure-anchored drug synonym record

All known targets

• AKT1
• AKT2
• AKT3

Mechanisms of action (all sources)

• AKT2 INHIBITOR
• Serine/threonine-protein kinase AKT inhibitor
• AKT3 INHIBITOR
• AKT1 INHIBITOR

Cross-references

• PubChem CID: 46843057
• ChEMBL: CHEMBL2219422
• DrugBank: DB11648
• ChEBI: 131168
• KEGG: D10381
• LINCS BRD: BRD-K25412176

Synonyms

• GSK-2110183
• ASB-183
• ASB183
• GSK-2110183C
• GSK2110183
• GSK2110183C
• GSK 2110183
• Afuresertib [USAN]
• Afuresertib (GSK2110183)
• Afuresertib (USAN)
• 8739X25QI3
• 2-Thiophenecarboxamide, N-((1S)-2-amino-1-((3-fluorophenyl)methyl)ethyl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-
• N-[(2S)-1-amino-3-(3-fluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-2-methylpyrazol-3-yl)thiophene-2-carboxamide
• Afuresertib [USAN:INN]
• UNII-8739X25QI3
• 2-Thiophenecarboxamide, N-[(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-
• N-((1S)-1-(aminomethyl)-2-(3-fluorophenyl)ethyl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide
• N-((2S)-1-AMINO-3-(3-FLUOROPHENYL)PROPAN-2-YL)-5-CHLORO-4-(4-CHLORO-1-METHYL-1H-PYRAZOL-5-YL)THIOPHENE-2-CARBOXAMIDE
• N-[(1S)-1-(Aminomethyl)-2-(3-fluorophenyl)ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide
• N-[(2S)-1-amino-3-(3-fluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide
• AFURESERTIB [INN]
• AFURESERTIB [WHO-DD]
• SCHEMBL187686
• GTPL7890
• CHEMBL2219422
• DTXSID60146711
• CHEBI:131168
• BCP08435
• EX-A1574
• BDBM50502477
• NSC778305
• NSC781255
• NSC800109
• NSC829868
• s7521
• ZINC43197674
• CCG-268972
• CS-3384
• DB11648