← SynDRA

CRENIGACESTAT

SynDRA canonical compound SYN0037052 — structure-anchored drug synonym record

All known targets

• NOTCH1
• NOTCH4
• NOTCH2
• NOTCH3

Mechanisms of action (all sources)

• notch signaling inhibitor
• NOTCH4 INHIBITOR
• NOTCH1 INHIBITOR

Cross-references

• PubChem CID: 71236992
• ChEMBL: CHEMBL2338397
• DrugBank: DB12050
• ChEBI: 232469
• KEGG: D11151
• PDB: N9C
• TTD: D08WOW

Synonyms

• JSMD-194
• JSMD194
• LY-3039478
• LY3039478
• UNII-923X28214S
• 4,4,4-Trifluoro-N-((S)-1-(((S)-5-(2-hydroxyethyl)-6-oxo-6,7-dihydro-5H-benzo[d]pyrido[2,3-b]azepin-7-yl)amino)-1-oxopropan-2-yl)butanamide
• 923X28214S
• butanamide, n-[(1s)-2-[[(7s)-6,7-dihydro-5-(2-hydroxyethyl)-6-oxo-5h-pyrido[3,2-a][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]-4,4,4-trifluoro-
• Butanamide, N-((1S)-2-(((7S)-6,7-dihydro-5-(2-hydroxyethyl)-6-oxo-5H-pyrido(3,2-a)(3)benzazepin-7-yl)amino)-1-methyl-2-oxoethyl)-4,4,4-trifluoro-
• LY 3039478
• crenigacestatum
• RefChem:919179
• BMS-986405
• Gamma-Secretase Inhibitor LY3039478
• Crenigacestat [USAN]
• MFCD26142650
• CRENIGACESTAT [INN]
• Crenigacestat (USAN/INN)
• CRENIGACESTAT [WHO-DD]
• orb1303976
• Crenigacestat (LY3039478)
• SCHEMBL14657256
• SCHEMBL29384049
• SCHEMBL29684828
• GTPL11359
• C22H23F3N4O4
• CHEBI:232469
• YCBAQKQAINQRFW-UGSOOPFHSA-N
• YCBAQKQAINQRFW-UGSOOPFHSA-O
• HMS3886L11
• EX-A1983
• NSC787253
• AKOS025291098
• CCG-269391
• CS-5807
• FT76166
• NSC-787253
• AC-32768
• HY-12449