← SynDRA
OSILODROSTAT
SynDRA canonical compound SYN0037812 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx |
|---|
| Primary target(s) | CYP11B1 | CYP11B2 |
|---|
| Mechanism of action | cytochrome P450 inhibitor |
|---|
All known targets
- CYP11B1
- CYP11B2
- CYP19A1
- Cyp11b1
- Cyp11b2
Mechanisms of action (all sources)
- CYP11B1 INHIBITOR
- Cytochrome P450 11B1 inhibitor
- cytochrome P450 inhibitor
- CYP11B1 MODULATOR
Drug classes
- Cytochrome P450 2D6 Inhibitors
- Cytochrome P450 1A2 Inhibitors
- Cytochrome P450 2C19 Inhibitors
- Cytochrome P450 3A4 Inhibitors
- Cytochrome P450 3A5 Inhibitors
- Cortisol Synthesis Inhibitor
- Cytochrome P450 11B1 Inhibitors
ATC classes
- H02C · ANTIADRENAL PREPARATIONS
Cross-references
Synonyms
- osilodrostat phosphate
- LCI699-NX
- LCI-699
- isturisa
- Lci-699
- Lci699
- LCI-699-NX
- LCI699
- LCI 699
- UNII-5YL4IQ1078
- CHEMBL3099695
- 5YL4IQ1078
- Osilodrostat;4-[(5R)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl]-3-fluorobenzonitrile
- Osilodrostat [USAN:INN]
- Osilodrostat (USAN/INN)
- GTPL8310
- SCHEMBL12460772
- DTXSID40156570
- MolPort-044-560-410
- EX-A1397
- ZINC72318114
- s7456
- BDBM50444549
- AKOS027323750
- DB11837
- CS-6896
- HY-16276
- KB-78108
- Z-3271
- D11061
- 4-[(5R)-6,7-Dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl]-3-fluorobenzo nitrile
- (+)-Osilodrostat
- osilodrostatum
- RefChem:56448
- DTXCID4079061
- H02CA02
- Osilodrostat (LCI699)
- Osilodrostat free base
Reported adverse events
- Blood testosterone increased
- Dizziness
- Fatigue
- Hypotension
- Myalgia
- Rash
- Tachycardia
- Vomiting
- Abdominal pain
- Adrenal insufficiency
- Arthralgia
- Back pain
Look up OSILODROSTAT in the interactive SynDRA portal →