← SynDRA

OSI-027

SynDRA canonical compound SYN0037823 — structure-anchored drug synonym record

All known targets

• MTOR
• MAPK8

Mechanisms of action (all sources)

• MAPK8 INHIBITOR
• MTOR inhibitor
• Serine/threonine-protein kinase mTOR inhibitor

Cross-references

• PubChem CID: 135398516
• ChEMBL: CHEMBL3120215
• DrugBank: DB12387
• ChEBI: 91363
• TTD: D1RLY2
• LINCS BRD: BRD-K87124298

Synonyms

• AEVI-006
• ASP-7486
• ASP7486
• CERC-006
• CERC006
• OSI027
• (+/-)-Cyclohexanecarboxylic acid, 4-(4-amino-5-(7-methoxy-1H-indol-2-yl)imidazo(5,1-f)(1,2,4)triazin-7-yl)-, trans-
• (1r,4r)-4-(4-Amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl)cyclohexane-1-carboxylic acid
• (1r,4r)-4-(4-amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl)cyclohexanecarboxylic acid
• (1r,4r)-4-(4-Amino-5-(7-methoxy-1H-indol-2-yl)imidazo-[5,1-f][1,2,4]triazin-7-yl)cyclohexanecarboxylic acid
• 25MKH1SZ0M
• 4-(4-Amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f] [1,2,4]Triazin-7-yl)cyclohexanecarboxylic Acid
• 4-[(5Z)-4-amino-5-(7-methoxyindol-2-ylidene)-1H-imidazo[5,1-f][1,2,4]triazin-7-yl]cyclohexane-1-carboxylic acid
• 4-[4-amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]cyclohexane-1-carboxylic acid
• 4-[4-amino-5-(7-methoxy-2-indolylidene)-1H-imidazo[5,1-f][1,2,4]triazin-7-yl]-1-cyclohexanecarboxylic acid
• 936890-98-1 (free acid)
• A-1065
• AC-31517
• AKOS030238938
• AKOS037643584
• AM81260
• AS-17003
• ASP4786
• BCP02613
• BCP9001034
• BDBM185151
• BRD-K94294671-003-01-3
• CCG-268721
• CHEBI:91363
• CHEMBL2132692
• CHEMBL3120215
• CS-0257
• Cyclohexanecarboxylic acid, 4-(4-amino-5-(7-methoxy-1H-indol-2-yl)imidazo(5,1-f)(1,2,4)triazin-7-yl)-, trans-
• Cyclohexanecarboxylic acid, 4-[4-amino-5-(7-methoxy-1h-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]-, trans-
• DB12387
• DTXSID901025951
• EX-A143
• F17371
• HMS3656H05