← SynDRA

FILGOTINIB

SynDRA canonical compound SYN0038037 — structure-anchored drug synonym record

All known targets

• JAK1
• JAK2
• JAK3
• TYK2
• AAK1
• ADCK1
• BMP2K
• CAMKK2
• CSF1R
• FLT3
• FLT4
• IRAK1

Mechanisms of action (all sources)

• JAK inhibitor
• JAK1 INHIBITOR
• Tyrosine-protein kinase JAK1 inhibitor
• JAK2 INHIBITOR
• Tyrosine-protein kinase JAK2 inhibitor
• TYK2 INHIBITOR
• Tyrosine-protein kinase TYK2 inhibitor
• JAK3 INHIBITOR
• Tyrosine-protein kinase JAK3 inhibitor
• JAK1 MODULATOR

ATC classes

• L04A · IMMUNOSUPPRESSANTS

Cross-references

• PubChem CID: 49831257
• ChEMBL: CHEMBL3301607
• DrugBank: DB14845
• KEGG: D11106
• PDB: 2HB
• Wikipedia: Filgotinib
• TTD: D0SG7B
• LINCS BRD: BRD-K16803204

Synonyms

• filgotinib maleate
• jyseleca
• filgotinib hydrochloride
• G-146034
• G-146034-101
• GLPG-0634
• FILGOTINIB (GLPG0634)
• Filgotinib hydrochloride
• FILGOTINIB??GLPG0643)
• FILGOTINIB（GLPG0643)
• G-146034_101
• G146034
• GLPG0634
• GS-6034 FREE BASE
• Small molecule, JAK1/JAK2 inhibitor (rheumatoid arthritis), Galapagos/GSK
• N-(5-(4-((1,1-dioxidothiomorpholino)methyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide
• GLPG 0634
• Filgotinib(GLPG0634)
• Filgotinib (GLPG0634)
• 3XVL385Q0M
• GPLG0634
• N-[5-[4-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide
• Jyseleca
• Filgotinib [INN]
• N-(5-(4-((1,1-dioxidothiomorpholino)methyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide.
• Filgotinib [USAN:INN]
• UNII-3XVL385Q0M
• N-(5-{4-[(1,1-Dioxidothiomorpholin-4-Yl)methyl]phenyl}[1,2,4]triazolo[1,5-A]pyridin-2-Yl)cyclopropanecarboxamide
• N-[5-[4-[(1,1-Dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide
• Filgotinib (USAN/INN)
• FILGOTINIB [USAN]
• Filgotinib; GPLG0634
• FILGOTINIB [WHO-DD]
• SCHEMBL253559
• Filgotinib pound GLPG0643)
• GTPL7913
• CHEMBL3301607
• AMY3802