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LUMATEPERONE
SynDRA canonical compound SYN0038078 — structure-anchored drug synonym record
Clinical phase
Launched
Approval status
Approved · Rx
Primary target(s)
DRD2 | HTR2A
Mechanism of action
dopamine receptor modulator | serotonin receptor antagonist
All known targets
DRD2
HTR2A
SLC6A4
ADRA1A
ADRA1B
DRD1
DRD4
Drd2
HTR1A
HTR2C
Mechanisms of action (all sources)
HTR2A ANTAGONIST
Serotonin 2a (5-HT2a) receptor antagonist
DRD2 ANTAGONIST
Dopamine D2 receptor antagonist
SLC6A4 INHIBITOR
Serotonin transporter inhibitor
dopamine receptor modulator
serotonin receptor antagonist
Drug classes
Atypical Antipsychotic
ATC classes
N05A · ANTIPSYCHOTICS
Cross-references
PubChem CID:
21302490
ChEMBL:
CHEMBL3306803
DrugBank:
DB06077
KEGG:
D11169
RxNorm:
2275602
PDB:
92S
Wikipedia:
Lumateperone
TTD: D1CWL0
Synonyms
lumateperone tosylate
caplyta
ITI-007
Lumateperona
ITI-722
ITI007
lumateperona
lumateperonum
RefChem:57789
DTXCID801510464
Lumateperone [USAN]
MFCD28502161
C24H28FN3O
Lumateperone?
ITI-722 lumateperone
Lumateperone(iti-007)
LUMATEPERONE [MI]
Lumateperone (USAN/INN)
LUMATEPERONE [INN]
LUMATEPERONE [WHO-DD]
orb1306463
SCHEMBL1468226
SCHEMBL29355930
UNII-70BSQ12069
HOIIHACBCFLJET-SFTDATJTSA-N
GLXC-15265
EX-A3605
BDBM50556204
EBC-26925
AKOS025396216
DS-8527
AC-38408
DA-74607
HY-17637
CS-0016831
NS00073380
D11169
T21069
Reported adverse events
Abdominal discomfort
Abdominal pain
Agranulocytosis
Akathisia
Depression
Dizziness
Dry mouth
Dyskinesia
Dysphagia
Dystonia
Fall
Fatigue
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