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TAZEMETOSTAT
SynDRA canonical compound SYN0038140 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx |
|---|
| Primary target(s) | EZH2 |
|---|
| Mechanism of action | histone lysine methyltransferase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- EZH2 INHIBITOR
- Histone-lysine N-methyltransferase EZH2 inhibitor
- histone lysine methyltransferase inhibitor
Drug classes
- Multidrug and Toxin Extrusion Transporter 1 Inhibitors
- Methyltransferase Inhibitor
- Methyltransferase Inhibitors
- Multidrug and Toxin Extrusion Transporter 2 K Inhibitors
ATC classes
- L01X · OTHER ANTINEOPLASTIC AGENTS
Cross-references
Synonyms
- tazemetostat hydrobromide
- tazverik
- EPZ-6438
- EZ438
- CT-EPZ438EPZ-6438EPZ6438A-1623E-7438E7438
- E-7438
- E7438
- EPZ6438
- TAZEMETOSTAT (EPZ-6438)
- EPZ 6438
- UNII-Q40W93WPE1
- N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4'-(morpholinomethyl)-[1,1'-biphenyl]-3-carboxamide
- Q40W93WPE1
- (1,1'-Biphenyl)-3-carboxamide, N-((1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl)-5-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4'-(4-morpholinylmethyl)-
- Tazemetostat [INN]
- E 7438
- Tazverik
- Tazemetostat [USAN]
- Tazemetostat(EPZ-6438)
- Tazemetostat (EPZ-6438)
- MFCD24849415
- N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-3-[ethyl(oxan-4-yl)amino]-2-methyl-5-[4-(morpholin-4-ylmethyl)phenyl]benzamide
- N-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl(oxan-4-yl)amino)-4-methyl-4'-((morpholin-4-yl)methyl)(1,1'-biphenyl)-3-carboxamide
- TAZEMETOSTAT [MI]
- Tazemetostat (USAN/INN)
- Tazemetostat [USAN:INN]
- TAZEMETOSTAT [WHO-DD]
- GTPL7011
- CHEMBL3414621
- SCHEMBL13276848
- SCHEMBL19325409
- SCHEMBL22210809
- EX-A509
- DTXSID201025831
- HMS3653O07
- HMS3747A09
- BCP07409
- NSC777109
Reported adverse events
- Abdominal pain
- Alopecia
- Constipation
- Cough
- Fatigue
- Headache
- Infection
- Lower respiratory tract infection
- Musculoskeletal pain
- Nausea
- Pain
- Pyrexia
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