← SynDRA

PREXASERTIB

SynDRA canonical compound SYN0038166 — structure-anchored drug synonym record

All known targets

• CHEK1
• CHEK2
• RPS6KA1

Mechanisms of action (all sources)

• CHEK1 INHIBITOR
• Serine/threonine-protein kinase Chk1 inhibitor
• CHEK2 INHIBITOR
• Serine/threonine-protein kinase Chk2 inhibitor
• RPS6KA1 INHIBITOR
• CHK inhibitor

Drug classes

• Protein Kinase Inhibitors

Cross-references

• PubChem CID: 46700756
• ChEMBL: CHEMBL3544911
• DrugBank: DB12008
• KEGG: D11206
• Wikipedia: Prexasertib
• TTD: D08UUL
• LINCS BRD: BRD-K20463415

Synonyms

• LY-2606368
• LY2606368
• UNII-820NH671E6
• 820NH671E6
• Prexasertib [USAN]
• 5-((5-(2-(3-aminopropoxy)-6-methoxyphenyl)-1H-pyrazol-3-yl)amino)pyrazine-2-carbonitrile
• 5-({5-[2-(3-aminopropoxy)-6-methoxyphenyl]-1H-pyrazol-3-yl}amino)pyrazine-2-carbonitrile
• 5-[[5-[2-(3-aminopropoxy)-6-methoxyphenyl]-1H-pyrazol-3-yl]amino]pyrazine-2-carbonitrile
• SCHEMBL1975451
• GTPL9549
• SCHEMBL19457660
• SCHEMBL18989301
• CHEMBL3544911
• EX-A758
• DOTGPNHGTYJDEP-UHFFFAOYSA-N
• AOB87325
• ZINC95837013
• Prexasertib (LY2606368)
• 5-(5-(2-(3-aminopropoxy)-6-methoxyphenyl)-1H-pyrazol-3-ylamino)pyrazine-2-carbonitrile
• LY2606368 mesylate monohydrate
• 2-Pyrazinecarbonitrile, 5-((5-(2-(3-aminopropoxy)-6-methoxyphenyl)-1H-pyrazol-3-yl)amino)-
• 2-Pyrazinecarbonitrile, 5-[[5-[2-(3-aminopropoxy)-6-methoxyphenyl]-1H-pyrazol-3-yl]amino]-
• PREXASERTIB [INN]
• Prexasertib (USAN/INN)
• LY2606368;Prexasertib
• PREXASERTIB [WHO-DD]
• DTXSID301031326
• BCP14380
• BDBM50524300
• MFCD25977016
• NSC758257
• NSC789570
• DB12008
• NSC-758257
• NSC-789570
• SB16662
• NCGC00390643-02
• NCGC00390643-06