← SynDRA

TEZACAFTOR

SynDRA canonical compound SYN0038169 — structure-anchored drug synonym record

All known targets

• CFTR

Mechanisms of action (all sources)

• CFTR POSITIVE MODULATOR
• Cystic fibrosis transmembrane conductance regulator positive modulator
• CFTR channel agonist
• CFTR BINDER
• CFTR PHARMACOLOGICAL CHAPERONE

ATC classes

• OTHER RESPIRATORY SYSTEM PRODUCTS

Cross-references

• PubChem CID: 46199646
• ChEMBL: CHEMBL3544914
• DrugBank: DB11712
• ChEBI: 234517
• KEGG: D11041
• RxNorm: 1999382
• PDB: CV6
• Wikipedia: Tezacaftor
• TTD: D0E1HC
• LINCS BRD: BRD-K97101532

Synonyms

• VX-661
• Tezacaftor component of symkevi
• Tezacaftor component of trikafta
• VX 661
• Tezacaftor (VX-661)
• Tezacaftor [USAN]
• (R)-1 (2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide
• VX661
• 8RW88Y506K
• 1-(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)-N-{1-[(2R)-2,3-DIHYDROXYPROPYL]-6-FLUORO-2-(1-HYDROXY-2-METHYLPROPAN-2-YL)INDOL-5-YL}CYCLOPROPANE-1-CARBOXAMIDE
• UNII-8RW88Y506K
• 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)indol-5-yl]cyclopropane-1-carboxamide
• CV6
• Cyclopropanecarboxamide, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-(1-((2R)-2,3-dihydroxypropyl)-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl)-
• TEZACAFTOR [MI]
• TEZACAFTOR [INN]
• Tezacaftor (USAN/INN)
• TEZACAFTOR [WHO-DD]
• SCHEMBL322362
• VX 661;VX661;Tezacaftor
• CHEMBL3544914
• SCHEMBL10034144
• TEZACAFTOR [ORANGE BOOK]
• GTPL10199
• DTXSID40673070
• BDBM281054
• SYMKEVI COMPONENT TEZACAFTOR
• BCP07173
• cyclopropanecarboxamide, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-n-[1-[(2r)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1h-indol-5-yl]-
• EX-A1759
• TRIKAFTA COMPONENT TEZACAFTOR
• MFCD23106064
• s7059
• US10022352, Compound 315
• ZINC68206930
• CCG-269854
• CS-1078
• DB11712