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SELINEXOR
SynDRA canonical compound SYN0038239 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx |
|---|
| Primary target(s) | XPO1 |
|---|
| Mechanism of action | exportin antagonist |
|---|
| Indication | multiple myeloma |
|---|
| Disease area | hematologic malignancy |
|---|
All known targets
Mechanisms of action (all sources)
- XPO1 INHIBITOR
- Exportin-1 inhibitor
- exportin antagonist
Drug classes
- Nuclear Export Inhibitor
- Nuclear Export Inhibitors
ATC classes
- L01X · OTHER ANTINEOPLASTIC AGENTS
Cross-references
Synonyms
- xpovio
- KPT-330
- Nexpovio
- Xpovio
- KPT-330(Selinexor)
- KPT330;Selinexor
- 31TZ62FO8F
- CHEMBL3545185
- SCHEMBL14678327
- Selinexor (KPT-330)
- Selinexor [USAN:INN]
- Tube706
- UNII-31TZ62FO8F
- KPT 330
- Selinexor free base
- (Z)-3-(3-(3,5-Bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyrazin-2-yl)acrylohydrazide
- 2-Propenoic acid, 3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-, 2-(2-pyrazinyl)hydrazide, (2Z)-
- (Z)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N'-pyrazin-2-ylprop-2-enehydrazide
- 2-Propenoic acid, 3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-, 2-(2-pyrazinyl)hydrazide, (2Z)-
- Selinexor [INN]
- Xpovio (TN)
- SELINEXOR [MI]
- Selinexor (USAN/INN)
- SELINEXOR [USAN]
- SELINEXOR [WHO-DD]
- SELINEXOR [ORANGE BOOK]
- GTPL10036
- EX-A870
- DTXSID801026013
- BDBM50527778
- MFCD27987944
- NSC780203
- NSC781780
- ZINC96170454
- CCG-269161
- DB11942
- NSC-780203
- NSC-781780
Reported adverse events
- Abdominal pain
- Cataract
- Cough
- Dehydration
- Dizziness
- Epistaxis
- Fatigue
- Headache
- Hypotension
- Infection
- Insomnia
- Leukopenia
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