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MK-5108

SynDRA canonical compound SYN0038334 — structure-anchored drug synonym record

All known targets

• AURKA
• AURKB
• AURKC

Mechanisms of action (all sources)

• aurora kinase inhibitor
• AURKA INHIBITOR
• Serine/threonine-protein kinase Aurora-A inhibitor
• AURKB INHIBITOR

Cross-references

• PubChem CID: 24748204
• ChEMBL: CHEMBL3600873
• DrugBank: DB12556
• ChEBI: 125340
• PDB: 5VC
• TTD: D0J6AB
• LINCS BRD: BRD-K53665955

Synonyms

• MK 5108
• MK5108
• VX-689
• VX 689
• MK-5108 (VX-689)
• UNII-H8J407531S
• VX689
• CHEMBL3600873
• H8J407531S
• 4-(3-chloro-2-fluorophenoxy)-1-[[6-(1,3-thiazol-2-ylamino)pyridin-2-yl]methyl]cyclohexane-1-carboxylic acid
• 4-(3-Chloranyl-2-Fluoranyl-Phenoxy)-1-[[6-(1,3-Thiazol-2-Ylamino)pyridin-2-Yl]methyl]cyclohexane-1-Carboxylic Acid
• (1r,4r)-4-(3-chloro-2-fluorophenoxy)-1-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)cyclohexane-1-carboxylic acid
• Cyclohexanecarboxylic acid,
• MK-5108/VX-689
• 4-(3-chloranyl-2-fluoranyl-phenoxy)-1-[[6-(1,3-thiazol-2-ylamino)pyridin-2-yl]methyl]cyclohexane-1-carboxylic acid