← SynDRA

LGH-447

SynDRA canonical compound SYN0038366 — structure-anchored drug synonym record

All known targets

• PIM1
• PIM2
• PIM3

Mechanisms of action (all sources)

• PIM1 INHIBITOR
• Serine/threonine-protein kinase PIM inhibitor
• PIM2 INHIBITOR
• PIM3 INHIBITOR
• Pim kinase inhibitor

Cross-references

• PubChem CID: 44814409
• ChEMBL: CHEMBL3651966
• DrugBank: DB14943
• PDB: 5H7
• TTD: D01QNR

Synonyms

• LGH 447
• PIM KINASE INHIBITOR LGH447
• 5HZ
• CPD 8
• LGH447
• NVP-LGH477
• PIM-447
• PIM447
• VRQXRVAKPDCRCI-ZNMIVQPWSA-N
• PIM447 (LGH447)
• N-{4-[(1r,3s,5s)-3-Amino-5-Methylcyclohexyl]pyridin-3-Yl}-6-(2,6-Difluorophenyl)-5-Fluoropyridine-2-Carboxamide
• N-[4-[(1R,3S,5S)-3-amino-5-methylcyclohexyl]pyridin-3-yl]-6-(2,6-difluorophenyl)-5-fluoropyridine-2-carboxamide
• UNII-9TG5O4V25H
• SCHEMBL3215332
• GTPL9790
• 9TG5O4V25H
• CHEMBL3651966
• PIM 447 [WHO-DD]
• BDBM106870
• ZINC116907270
• AKOS032945086
• CS-5929
• compound 8 [PMID: 26505898]
• HY-19322
• J3.552.648J
• US8592455, 70
• 5H7
• 2-Pyr
• PIM 447
• Pim kinase inhibitor lgh447
• RefChem:153262
• PIM447 dihydrochloride
• LGH447-(1S,3R,5R)
• LGH447 2HCl
• LGH-447 2HCl
• orb1708852
• SCHEMBL29379725
• PIM447; LGH447
• GLXC-10644