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PEXIDARTINIB
SynDRA canonical compound SYN0038563 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx |
|---|
| Primary target(s) | CSF1R | FLT3 | KIT |
|---|
| Mechanism of action | tyrosine kinase inhibitor |
|---|
All known targets
- CSF1R
- FLT3
- KIT
- CDK19
- FLT1
- KDR
- LCK
- NTRK3
- AAK1
- AURKB
- Csf1r
- PDGFRA
Mechanisms of action (all sources)
- CSF1R INHIBITOR
- Macrophage colony stimulating factor receptor inhibitor
- FLT3 INHIBITOR
- Tyrosine-protein kinase receptor FLT3 inhibitor
- KIT INHIBITOR
- Stem cell growth factor receptor inhibitor
- CDK19 INHIBITOR
- FLT1 INHIBITOR
- KDR INHIBITOR
- LCK INHIBITOR
- NTRK3 INHIBITOR
- tyrosine kinase inhibitor
Drug classes
- Tyrosine Kinase Inhibitors
- Colony Stimulating Factor Receptor Type 1 (CSF-1R) Inhibitors
- Kinase Inhibitors
- Kinase Inhibitor
- Cytochrome P450 2B6 Inhibitors
- Cytochrome P450 3A Inducers
- UGT1A1 Inhibitors
ATC classes
- L01E · PROTEIN KINASE INHIBITORS
Cross-references
Synonyms
- pexidartinib hydrochloride
- PLX3397
- CML-261
- turalio
- PLX-3397
- PEXIDARTINIB (PLX3397)
- PEXIDARTINIBPLX-3397
- PLX 3397
- pexidartinibum
- CHEBI:145373
- RefChem:57219
- DTXCID701510659
- Pexidartinib (PLX3397)
- Turalio
- Pexidartinib [INN]
- MFCD28900745
- Pexidartinib [USAN]
- UNII-6783M2LV5X
- PEXIDARTINIB [MI]
- Pexidartinib (USAN/INN)
- Pexidartinib [USAN:INN]
- Pexidartinib(PLX3397)?
- C20H15ClF3N5
- PEXIDARTINIB [WHO-DD]
- GTPL8710
- orb1306449
- SCHEMBL1267310
- SCHEMBL29361827
- SCHEMBL29380288
- EX-A589
- JGWRKYUXBBNENE-UHFFFAOYSA-N
- GLXC-90308
- HMS3886D19
- HMS5085F22
- BDBM50177716
- EBC-17101
- HB8991
- NSC789300
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