← SynDRA

LY-2874455

SynDRA canonical compound SYN0038570 — structure-anchored drug synonym record

All known targets

• FGFR2
• FGFR1
• FGFR3
• FGFR4
• KDR

Mechanisms of action (all sources)

• FGFR3 INHIBITOR
• Fibroblast growth factor receptor inhibitor
• FGFR1 INHIBITOR
• FGFR4 INHIBITOR
• FGFR2 INHIBITOR
• FGFR antagonist
• FGFR2 MODULATOR

Cross-references

• PubChem CID: 46944259
• ChEMBL: CHEMBL3828009
• DrugBank: DB13022
• PDB: 6LF
• TTD: D0D4VV

Synonyms

• LY2874455
• LY 2874455
• UNII-E9M363811V
• CHEMBL3828009
• E9M363811V
• AK186860
• (R,E)-2-(4-(2-(5-(1-(3,5-Dichloropyridin-4-yl)-ethoxy)-1H-indazol-3-yl)vinyl)-1H-pyrazol-1-yl)ethanol
• C21H19Cl2N5O2
• (R,E)-2-(4-(2-(5-(1-(3,5-dichloropyridin-4-yl)ethoxy)-1H-indazol-3-yl)vinyl)-1H-pyrazol-1-yl)ethanol
• GKJCVYLDJWTWQU-CXLRFSCWSA-N
• SCHEMBL298446
• SCHEMBL298445
• QCR-90
• GTPL8104
• DTXSID20154776
• MolPort-044-724-281
• MolPort-023-219-117
• EX-A1340
• BCP04756
• ZINC73069242
• BDBM50189781
• 2529AH
• s7057
• AKOS027251051
• 1H-Pyrazole-1-ethanol, 4-((1E)-2-(5-((1R)-1-(3,5-dichloro-4-pyridinyl)ethoxy)-1H-indazol-3-yl)ethenyl)-
• 2-[4-[(E)-2-[5-[(1R)-1-(3,5-dichloropyridin-4-yl)ethoxy]-1H-indazol-3-yl]ethenyl]pyrazol-1-yl]ethanol
• (R,E)-2-(4-(2-(5-(1-(3,5-dichloropyridin-4-yl)ethoxy)-1H-indazol-3-yl)vinyl)-1H-pyrazol-1-yl)ethanol.
• LY2874455 monohydrate
• NSC771750
• NSC783670
• BCP9000878
• CCG-269169
• CS-0907
• DB13022
• LM 1476
• NSC-771750
• NSC-783670
• (R)-(E)-2-(4-(2-(5-(1-(3,5-Dichloropyridin-4-yl)ethoxy)-1H-indazol-3-yl)vinyl)-1H-pyrazol-1-yl)ethanol
• (R,E)-2-(4-(2-(5-(1-(3,5-dichloropyridin-4-yl)ethoxy)-1H-indazol-3-yl)vinyl)-1H-pyrazol-1-yl)ethan-1-ol