SITRAVATINIB

SynDRA canonical compound SYN0039153 — structure-anchored drug synonym record

Clinical phase	Phase 3
Primary target(s)	AXL \| DDR1 \| DDR2 \| EPHA2 \| EPHA4 \| EPHB2 \| EPHB4 \| EPHB6 \| FLT1 \| FLT3 \| FLT4 \| KDR \| KIT \| MERTK \| MET \| NTRK1 \| RET \| TEK
Mechanism of action	receptor tyrosine protein kinase inhibitor

All known targets

MET
KDR
FLT4
AXL
FLT1
RET
NTRK1
MERTK
KIT
FLT3
DDR2
DDR1

Mechanisms of action (all sources)

AXL INHIBITOR
DDR2 INHIBITOR
EPHA3 INHIBITOR
FLT1 INHIBITOR
FLT3 INHIBITOR
FLT4 INHIBITOR
KDR INHIBITOR
KIT INHIBITOR
MERTK INHIBITOR
MET INHIBITOR
NTRK1 INHIBITOR
PDGFRA INHIBITOR

ATC classes

L01E · PROTEIN KINASE INHIBITORS

Cross-references

PubChem CID: 25212148
ChEMBL: CHEMBL3989926
DrugBank: DB15036
KEGG: D11140
Wikipedia: Sitravatinib
TTD: D05BLN

Synonyms

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