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DIROXIMEL FUMARATE
SynDRA canonical compound SYN0039169 — structure-anchored drug synonym record
| Clinical phase | Phase 3 |
|---|
| Approval status | Approved · Rx |
|---|
| Primary target(s) | HCAR2 |
|---|
| Mechanism of action | anti-inflammatory agent |
|---|
All known targets
Mechanisms of action (all sources)
- KEAP1 INHIBITOR
- Kelch-like ECH-associated protein 1 inhibitor
- anti-inflammatory agent
ATC classes
- L04A · IMMUNOSUPPRESSANTS
Cross-references
Synonyms
- vumerity
- ALKS 8700
- RDC-5108
- Diroximel fumarate (biib098)
- Fumarate de diroximel
- Fumarato de diroximel
- ALKS-8700
- ALKS8700
- BIIB-098
- BIIB098
- RDC5108
- Vumerity
- 2-(2,5-Dioxopyrrolidin-1-yl)ethyl methyl fumarate
- UNII-K0N0Z40J3W
- K0N0Z40J3W
- Diroximel Fumarete
- Diroximel fumarate [INN]
- SCHEMBL15499960
- CHEMBL3989944
- SCHEMBL15511916
- Diroximel fumarate [USAN:INN]
- MolPort-046-033-659
- Diroximel Fumarete(ALKS-8700)
- ZINC215286156
- AKOS027256112
- AS-55046
- TZ001258
- 2-(2,5-Dioxopyrrolidin-1-yl)ethyl methyl (2E)-but- 2-enedioate
- 2-Butenedioic acid (2E)-, 1-(2-(2,5-dioxo-1-pyrrolidinyl)ethyl) 4-methyl ester
- fumarate de diroximel
- fumarato de diroximel
- diroximeli fumaras
- RefChem:58340
- DTXCID301510433
- MFCD28502263
- Vumerity (TN)
- orb1303002
Reported adverse events
- Abdominal pain
- Alopecia
- Angioedema
- Aspartate aminotransferase increased
- Dyspepsia
- Erythema
- Flushing
- Herpes zoster
- Infection
- Lymphopenia
- Nausea
- Pruritus
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