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PEXMETINIB
SynDRA canonical compound SYN0039227 — structure-anchored drug synonym record
| Clinical phase | Phase 1 |
|---|
| Primary target(s) | MAPK14 | TEK |
|---|
| Mechanism of action | MAP kinase inhibitor | TIE tyrosine kinase inhibitor |
|---|
All known targets
- TEK
- MAPK14
- ABL1
- ABL2
- FGFR1
- FLT1
- FLT4
- FYN
- HCK
- LYN
- MAPK11
- MINK1
Mechanisms of action (all sources)
- MAPK14 INHIBITOR
- MAP kinase p38 alpha inhibitor
- TEK INHIBITOR
- Tyrosine-protein kinase TIE-2 inhibitor
- ABL1 INHIBITOR
- ABL2 INHIBITOR
- FGFR1 INHIBITOR
- FLT1 INHIBITOR
- FLT4 INHIBITOR
- FYN INHIBITOR
- HCK INHIBITOR
- LYN INHIBITOR
Cross-references
Synonyms
- ARRY-614
- Pexmetinib (ARRY-614)
- UNII-3750D0U8B5
- 3750D0U8B5
- Pexmetinib [INN]
- Pexmetinib;ARRY-614
- Pexmetinib(ARRY-614)
- ARRY614
- SCHEMBL379035
- GTPL9917
- MolPort-039-193-822
- LNMRSSIMGCDUTP-UHFFFAOYSA-N
- BCP28410
- EX-A1421
- s7799
- ZINC41747181
- AKOS032945154
- SB16914
- Urea, N-(3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl)-N'-((5-fluoro-2-((1-(2-hydroxyethyl)-1H-indazol-5-yl)oxy)phenyl)methyl)-
- pexmetinibum
- RefChem:172186
- A1AWV
- C31H33FN6O3
- MFCD28502055
- Pexmetinib(ARRY-614)?
- PEXMETINIB [WHO-DD]
- orb1300332
- SCHEMBL29353601
- GLXC-10853
- BDBM50563437
- EBC-24091
- NSC778367
- NSC800844
- CCG-270035
- NSC-778367
- NSC-800844
- NCGC00481573-01
- NCGC00481573-02
- AC-36569
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